Results 71 to 80 of about 792 (225)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

On Axiomatization of Non-Cartesian Logics

, 2012
Nowadays it is generally accepted as a kind of truism by a significant part of logicians that Belnap's four-valued logic B4 (the definition see below) is a good logical system, which is both useful in practice and fruitful in theory.
Prelovskiy, Nikolay
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

On the Licensing of Understating NPIs: Manipulating the domain of degrees for Japanese \u27anmari\u27 and \u27sonnani\u27

, 2011
Negative Polarity Items (NPIs) often have an effect of strengthening the statements which contain them. However, there are also NPIs that contribute to make a weaker claim such as all that (Israel 1996, 2006; van Rooy 2003).
Matsui, Ai
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Identifying the Question Similarity of Regulatory Documents in the Pharmaceutical Industry by Using the Recognizing Question Entailment System: Evaluation Study. [PDF]

JMIR AI, 2023
Saraswat N, Li C, Jiang M.
europepmc   +1 more source

A simple Henkin-style completeness proof for Gödel 3-valued logic G3 [PDF]

[EN] A simple Henkin-style completeness proof for Gödel 3-valued propositional logic G3 is provided. The idea is to endow G3 with an under-determined semantics (u-semantics) of the type defined by Dunn.
Robles Vázquez, Gemma
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Logical Grounding and First-Degree Entailments [PDF]

Grazer Philosophische Studien, 2015
openaire   +2 more sources

Revisitando a Lógica de Dunn-Belnap

, 2017
O presente artigo apresenta uma semântica baseada nas atitudes cognitivas de aceitação e rejeição por uma sociedade de agentes para lógicas inspiradas no First Degree Entailment (E) de Dunn e Belnap.
Blasio, Carolina
core