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Depression in first-episode schizophrenia
American Journal of Psychiatry, 1993Because findings regarding the prognostic significance of depressive symptoms in schizophrenia and their effect on the course and treatment of schizophrenia have been limited by the effects of previous treatment, retrospective evaluations, and differing definitions and criteria, the authors sought to determine the prevalence and prognostic significance
A R, Koreen +5 more
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First-Episode Major Depression
Archives of General Psychiatry, 1997There is a sex difference in the prevalence of unipolar major depression. This study sought to determine whether there is a sex difference in its course.The National Institute of Mental Health Collaborative Program on the Psychobiology of Depression-Clinical Studies provided data on 96 male and 101 female subjects who were diagnosed as having a first ...
H B, Simpson, J C, Nee, J, Endicott
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Family environment and depressive episode are associated with relapse after first‐episode psychosis
Journal of Psychiatric and Mental Health Nursing, 2021Accessible summaryWhat is known on the subject? Relapse rates are high among patients who have experienced first‐episode psychosis (FEP). Psychotic relapses are associated with worse quality of life and poorer functionality of the FEP patient. The use of psychoactive substances, non‐adherence to drug treatment, and high expressed emotion (EE) are ...
Amanda Heloisa Santana da Silva +6 more
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Depression in people with first-episode schizophrenia
British Journal of Psychiatry, 1998Background Depression has been described in people presenting with first-episode schizophrenia, a group at high relative risk of suicide.Method This was a longitudinal cohort study of 113 people during an acute relapse and 13 having a first episode. Follow-up occurred at three months and at one year.
D, Addington, J, Addington, S, Patten
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Hippocampal volume in first episode and recurrent depression
Psychiatry Research: Neuroimaging, 2009Abnormalities in limbic-thalamic-cortical networks are hypothesized to modulate human mood states. In the present study differences in hippocampal volumes of patients with a first episode of depression, recurrent major depression and healthy control subjects were examined with high-resolution magnetic resonance imaging (MRI). Male patients with a first
Klaus-Thomas, Kronmüller +10 more
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Treatment preferences in patients with first episode depression
Journal of Affective Disorders, 2013Treatment preferences of patients suffering from depression may affect adherence and clinical outcomes. This study examines associations between patients' treatment preferences, their characteristics and illness representations of depression.Illness representations of depression (IPQ-R), treatment acceptability and preferences were assessed in 88 newly
Houle, Janie +5 more
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Depressive symptoms in first episode schizophrenia spectrum disorder
Schizophrenia Research, 2012Depressive symptoms in 'non-affective' first episode schizophrenia spectrum disorders (FES) are common, but poorly understood, resulting in a range of conceptual and clinical management issues. This study had three aims: (i) to determine the prevalence of moderate to severe depressive symptoms (defined as a Clinical Global Impressions Scale-Bipolar ...
Cotton, Sue +9 more
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Information processing in patients with first episode major depression
Scandinavian Journal of Psychology, 2012Hammar, Å., Kildal, A. B. & Schmid, M. (2012). Information processing in patients with first episode major depression. Scandinavian Journal of Psychology 53, 445–449.Few studies have investigated cognitive functioning in a group of patients experiencing a first episode of depression.
Åsa, Hammar +2 more
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Two-year outcomes in first-episode psychotic depression the McLean-Harvard First-Episode Project.
Journal of affective disorders, 2012Early assessment can guide accurate diagnosis, prognosis, and treatment-planning for patients with major mental illnesses. Longitudinal studies in psychotic depression from onset are rare, encouraging the present study.We followed 56 DSM-IV MDD patients with psychotic features prospectively and systematically to assess course and predictors of ...
Tohen M +5 more
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