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Increased Bone Remodeling in First-Episode Major Depressive Disorder

Psychosomatic Medicine, 2000
Bone mineral density is decreased in patients with depressive disorder. This study evaluated biochemical bone remodeling markers in patients having their first depressive episode who had not taken psychotropic medications to evaluate possible pathogenic mechanisms implicated in the loss of bone mineral density in early states of this illness.Serum ...
A, Herrán   +5 more
openaire   +2 more sources

Higher-order social cognition in first-episode major depression

Psychiatry Research, 2014
Patients suffering from major depression experience difficulties in multiple cognitive faculties. A growing body of research has linked affective disorders to abnormalities in social cognition and specifically the processing of discrete emotional stimuli.
Nicolai Ladegaard   +3 more
openaire   +3 more sources

Does bereavement-related first episode depression differ from other kinds of first depressions?

Social Psychiatry and Psychiatric Epidemiology, 2009
It has never been investigated whether first depression differs in patients who have experienced bereavement compared to patients who have not.Patients discharged with a diagnosis of a single depressive episode from a psychiatric in- or outpatient hospital setting were consecutively sampled from the Danish Psychiatric Central Research Register ...
Kessing, Lars Vedel   +4 more
openaire   +3 more sources

Convergent molecular and structural neuroimaging signatures of first-episode depression

Journal of Affective Disorders, 2023
Convergent studies have demonstrated morphological abnormalities in various brain regions in depression patients. However, the molecular underpinnings of the structural impairments remain largely unknown, despite a pressing need for treatment targets and mechanisms.
Yuan, Chen   +11 more
openaire   +2 more sources

EEG microstate in first-episode drug-naive adolescents with depression

Journal of Neural Engineering, 2022
Abstract A growing number of studies have revealed significant abnormalities in electroencephalography (EEG) microstate in patients with depression, but these findings may be affected by medication. Therefore, how the EEG microstates abnormally change in patients with depression in the early stage and without the influence of ...
Zongya Zhao   +13 more
openaire   +2 more sources

Childhood trauma in recurrent and first episode depression

Anatolian Journal of Psychiatry, 2013
Objective: The aim of this study is to compare patients who have recurrent and first episode major depressive disorder and healthy controls based upon their childhood traumas. Methods: Sixty subjects with the diagnoses of primarily as Major Depressive Disorder according to DSM-IV-TR who admitted Bezm-i Alem Valide Sultan Vakif Gureba Education and ...
Feridun Bulbul   +5 more
openaire   +1 more source

Neuropsychological Dysfunction in Antipsychotic-Naive First-Episode Unipolar Psychotic Depression

American Journal of Psychiatry, 2004
The profile of neuropsychological impairment associated with unipolar psychotic depression remains unclear. The authors used a neuropsychological test battery to characterize the neuropsychiatric profile of patients with unipolar psychotic depression, relative to that of patients with nonpsychotic unipolar depression, patients with schizophrenia, and ...
S Kristian, Hill   +3 more
openaire   +2 more sources

Emotional information processing in first and recurrent major depressive episodes

Journal of Psychiatric Research, 2004
Depressive states are classically associated to increased sensitivity to negative events. However this hypersensitivity may not be stable in time, being absent in remission periods or further reinforced with recurrent depressive episodes, or may concern positive stimuli instead, e.g. in young depressive patients.
Nandrino, Jean-Louis   +3 more
openaire   +5 more sources

Rorschach Findings and Neuropsychological Comparison of First-Episode Psychotic Depression with First-Episode Nonpsychotic Depression and Schizophrenia: A Preliminary Report

Rorschachiana, 1997
Dans cette étude nous avons tenté de clarifier les traits neuropsychologiques et l’organisation psychologique qui différencient la dépression psychotique. Nous avons comparé 17 psychotiques unipolaires déprimés dans leur premier épisode avec 14 patients non psychotiques déprimés dans leur premier épisode et 20 patients schizophrènes, en utilisant une ...
Tuula Ilonen   +2 more
openaire   +1 more source

Manic and depressive symptoms and insight in first episode psychosis

Psychiatry Research, 2010
Insight impairment is common early in the course of psychosis. Most studies have focused on the relationship between insight and depression, although manic symptoms are also frequent in psychoses. The main aim of this study was to examine the relationship between insight dimensions and manic and depressive symptoms in first-episode psychosis.
Saioa, Aspiazu   +9 more
openaire   +2 more sources

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