Results 41 to 50 of about 13,588,695 (290)

Comparison of sleep structure in patients with different types of major mental disorders and its establishment of prediction model

Huli yanjiu, 2023
ObjectiveTo explore the difference of sleep structure among patients with different types of major mental disorders，and to build prediction model.MethodsA total of 100 patients with schizophrenia，100 patients with bipolar disorder and 223 patients with ...
LI Kaiwen, LANG Xiao'e, LIU Cai, HAO Meng   +3 more
doaj  

Severity of Depressive Symptoms is Associated with Venous Thromboembolism in Hospitalized Patients with a Major Depressive Episode

Neuropsychiatric Disease and Treatment, 2021
Kazuhisa Yoshizawa,1 Masahiro Takeshima,2 Sayaka Ishino,3 Masaya Ogasawara,2 Dai Fujiwara,2 Yu Itoh,2 Aya Imanishi,2 Hidenobu Ohta,2 Kazuo Mishima2 1Department of Psychiatry, Akita Prefectural Center for Rehabilitation and Psychiatric Medicine, Daisen ...
Yoshizawa K, Takeshima M, Ishino S, Ogasawara M, Fujiwara D, Itoh Y, Imanishi A, Ohta H, Mishima K   +8 more
doaj  

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

Amygdala functional connectivity in female patients with major depressive disorder with and without suicidal ideation

Annals of General Psychiatry, 2018
Background Major depressive disorder (MDD) is a known major risk factor for suicide and is one of the most common mental disorders. Meanwhile, gender differences in suicidal behavior have long been recognized including the finding that women have higher ...
Shengnan Wei, Miao Chang, Ran Zhang, Xiaowei Jiang, Fei Wang, Yanqing Tang   +5 more
doaj   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

Functional abnormalities in first-episode major depressive disorder with somatic pain

Journal of Affective Disorders Reports, 2020
Objective: Depression has a high incidence of somatic pain, and the mechanism of pain in depressed patients remains unclear. Our study explored brain areas with abnormal activity in first-episode major depressive disorder with somatic pain using resting ...
Jiaquan Liang, Hairong Liao, Xiaoling Li, Caixia Xu, Zhenyu Xu, Yang Yu, Hui Zhou, Xiaobing Lu, Guojun Xie   +8 more
doaj   +1 more source

A case presenting with a major depressive episode with palilalia and difficulty opening eyes as prodromal symptoms of progressive supranuclear palsy

PCN Reports, 2022
Background Progressive supranuclear palsy (PSP) is a neurodegenerative disease and patients with PSP frequently experience depression. However, there have been few reports of patients with major depressive disorder as an antecedent diagnosis of PSP. Here,
Koji Matsuzawa, Yuichi Yokoyama, Yuichiro Watanabe, Takahiro Wakasugi, Toshiyuki Someya   +4 more
doaj   +1 more source

The predictive factors of subjective recovery in first-episode psychosis. [PDF]

, 2007
Conceptualisations of recovery from psychosis have evolved over time, from medically defined models of symptom reduction, to more recent definitions of subjective recovery. First-episode psychosis (FEP) individuals present as a group who are in the early
Morland, T.
core  

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky, Melissa Lopez, Janet Miller, Millenia Jimenez, Eric M. Liotta, Igor J. Koralnik   +5 more
wiley   +1 more source