Results 31 to 40 of about 1,011,813 (298)

Connectivity-enhanced diffusion analysis reveals white matter density disruptions in first episode and chronic schizophrenia. [PDF]

open access: yes, 2018
Reduced fractional anisotropy (FA) is a well-established correlate of schizophrenia, but it remains unclear whether these tensor-based differences are the result of axon damage and/or organizational changes and whether the changes are progressive in the ...
Bearden, Carrie E   +6 more
core   +3 more sources

Predictors of engagement in first-episode psychosis [PDF]

open access: yes, 2016
Engagement with psychiatric services is critical for ensuring successful outcomes in patients experiencing a first episode of psychosis (FEP). However, it is not known how sociodemographic factors and patient beliefs about the causes of mental illness ...
Birchwood, M. J.   +8 more
core   +1 more source

Dorsal striatal hypoconnectivity predicts antipsychotic medication treatment response in first‐episode psychosis and unmedicated patients with schizophrenia

open access: yesBrain and Behavior, 2022
Introduction The dorsal striatum, comprised of the caudate and putamen, is implicated in the pathophysiology of psychosis spectrum disorders. Given the high concentration of dopamine receptors in the striatum, striatal dopamine imbalance is a likely ...
Eric A. Nelson   +4 more
doaj   +1 more source

Aberrant posterior cingulate connectivity classify first-episode schizophrenia from controls: A machine learning study

open access: yes, 2020
Background Posterior cingulate cortex (PCC) is a key aspect of the default mode network (DMN). Aberrant PCC functional connectivity (FC) is implicated in schizophrenia, but the potential for PCC related changes as biological classifier of schizophrenia ...
Deng, W.   +14 more
core   +1 more source

Diabetes in first manic episode

open access: yesPsychiatry and Behavioral Sciences, 2013
Objective: The aim of this study was to investigate the frequency of diabetes during the first manic episode and explore, whether a relationship between diabetes and clinical features of mania exists or not.
Ali Gorkem Gencer   +2 more
doaj   +1 more source

Neural correlates of executive function and working memory in the 'at risk mental state' [PDF]

open access: yes
Background and Aims: People with ‘prodromal’ symptoms have a very high risk of developing psychosis. We used functional MRI to examine the neurocognitive basis of this vulnerability.
Brammer, M. J. (Mick J.)   +11 more
core   +1 more source

Symptoms at onset in first episode schizophrenia: Caregivers perspectives

open access: yesIndian Journal of Psychological Medicine, 2015
Background: Early recognition of symptoms is important in the management of psychosis. Caregivers understanding and attribution of symptoms plays a major role in treatment selection. Aim: The aim was to identify the various symptoms cluster recognized by
Hema Tharoor, Aarthi Ganesh
doaj   +1 more source

Gender differences in first episode psychotic mania [PDF]

open access: yes, 2013
Background : The aim of this paper was to delineate the impact of gender on premorbid history, onset, and 18 month outcomes of first episode psychotic mania (FEPM) patients. Methods : Medical file audit assessment of 118 (male = 71; female = 47) patients
A Bechdolf   +62 more
core   +2 more sources

Retrospective study on structural neuroimaging in first-episode psychosis [PDF]

open access: yesPeerJ, 2016
Background. No consensus between guidelines exists regarding neuroimaging in first-episode psychosis. The purpose of this study is to assess anomalies found in structural neuroimaging exams (brain computed tomography (CT) and magnetic resonance imaging ...
Ricardo Coentre   +2 more
doaj   +2 more sources

Stigma and access to care in first-episode psychosis [PDF]

open access: yes, 2019
Aim Mental health‐related stigma is considered a significant barrier to help‐seeking and accessing care in those experiencing mental illness. Long duration of untreated psychosis is associated with poorer outcomes. The impact of stigma on the duration
Birchwood, M. J.   +7 more
core   +1 more source

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