Results 41 to 50 of about 1,010,502 (197)

Dorsal striatal hypoconnectivity predicts antipsychotic medication treatment response in first‐episode psychosis and unmedicated patients with schizophrenia

Brain and Behavior, 2022
Introduction The dorsal striatum, comprised of the caudate and putamen, is implicated in the pathophysiology of psychosis spectrum disorders. Given the high concentration of dopamine receptors in the striatum, striatal dopamine imbalance is a likely ...
Eric A. Nelson, Nina V. Kraguljac, Jose O. Maximo, William Armstrong, Adrienne C. Lahti   +4 more
doaj   +1 more source

Gender differences in first episode psychotic mania [PDF]

, 2013
Background : The aim of this paper was to delineate the impact of gender on premorbid history, onset, and 18 month outcomes of first episode psychotic mania (FEPM) patients. Methods : Medical file audit assessment of 118 (male = 71; female = 47) patients
A Bechdolf, A Diflorio, A Thorup, B Dell'Osso, Benno G Schimmelmann, BF Grant, BG Schimmelmann, BG Schimmelmann, BG Schimmelmann, BG Schimmelmann, BI Goldstein, BI Goldstein, CA Macneil, CF Baldassano, CS Meade, E Dunayevich, E Liebenluft, Early Psychosis Prevention and Intervention Centre (EPPIC), F Jaworski, Felicity J Butselaar, G Davidson, H Fisher, H Hafner, H Hafner, I Kawa, J Robinson, J Robinson, JD Lish, K Suominen, KL McCabe, L Miquel, LL Altshuler, LM Arnold, M Berk, M Berk, M Bertani, M Lambert, M Lambert, M Shevlin, M Tohen, Martin Lambert, Michael Berk, N Kennedy, N Pereda, P Braunig, P Conus, P Conus, P Conus, P Conus, P Conus, Patrick D McGorry, PD McGorry, PE Bebbington, Philippe Conus, S Archie, S Fazel, S Romero, S Secunda, SM Cotton, Sue M Cotton, TV Lagerberg, W Guy, WM Compton   +62 more
core   +2 more sources

Neurocognitive functioning and emotional recognition in first-episode psychosis: protocol for a follow- up study

European Psychiatry
Introduction Although deficits in neurocognitive functioning and emotional recognition impact treatment outcomes in schizophrenia since the development of the first psychotic episode (FEP), there is still a lack of longer follow-up studies showing the ...
D. Bošnjak Kuharić, P. Makaric, K. Brozic, L. Tomasic, A. Savic, D. Ostojic, M. Rojnic Kuzman   +6 more
doaj   +1 more source

Proxy measures for the assessment of psychotic and affective symptoms in studies using electronic health records

BJPsych Open
Background There is a lack of standardised psychometric data in electronic health record (EHR)-based research. Proxy measures of symptom severity based on patients' clinical records may be useful surrogates in mental health EHR research. Aims This study
Álvaro López-Díaz, Fernanda Jazmín Palermo-Zeballos, Luis Gutierrez-Rojas, Luis Alameda, Francisco Gotor-Sánchez-Luengo, Nathalia Garrido-Torres, Johann Métrailler, Livia Alerci, Vincent Bonnarel, Pablo Cano-Domínguez, Elma Avanesi-Molina, Miguel Soto-Ontoso, Rocio Torrecilla-Olavarrieta, Leticia Irene Muñoz-Manchado, Pedro Torres-Hernández, Fermín González-Higueras, Juan Luis Prados-Ojeda, Mario Herrera-Cortés, José Miguel Meca-García, Rafael Manuel Gordillo-Urbano, Cristina Sánchez-Robles, Tomás Delgado-Durán, María Felipa Soriano-Peña, Philippe Golay, Philippe Conus, Benedicto Crespo-Facorro, Miguel Ruiz-Veguilla   +26 more
doaj   +1 more source

Hippocampal Volumes in First-Episode Psychosis [PDF]

The Journal of Neuropsychiatry and Clinical Neurosciences, 2009
Studies have shown that patients with schizophrenia have smaller hippocampi than healthy comparison subjects. There are, however, inconsistencies regarding the relationship between clinical characteristics and topographical differences in hippocampal volumetry.
Verma, Swapna, Sitoh, Yih-Yian, Ho, Yi Ching Lynn, Poon, Lye-Yin, Subramaniam, Mythily, Chan, Yiong-Huak, Sim, Kang, Chong, Siow-Ann   +7 more
openaire   +3 more sources

The striatal dopamine transporter in first-episode, drug-naive schizophrenic patients: evaluation by the new SPECT-ligand[99mTc]TRODAT-1 [PDF]

, 2005
Following the current hypothesis that acute schizophrenic psychotic illness is associated with a triatal ‘hyperdopaminergic state’, presynaptic integrity and dopamine transporter (DAT) density in first-episode, neuroleptic-naive schizophrenic patients ...
Abi-Dargham A, Bannon M J, C. La Fougère, Ciliax B J, Dresel S H, E. M. Meisenzahl, G. J. E Schmitt, H- J. Möller, K. Hahn, Kuikka J T, Mozley P, Mozley P, S. Dresel, T. Frodl   +13 more
core   +1 more source

Modular Functional-Metabolic Coupling Alterations of Frontoparietal Network in Schizophrenia Patients

Frontiers in Neuroscience, 2019
Background: Brain functional dysconnectivity, as well as altered network organization, have been demonstrated to occur in schizophrenia. Brain networks are increasingly understood to exhibit modular community structures, which provides advantages in ...
Qiong Xiang, Jiale Xu, Jiale Xu, Yingchan Wang, Tianyi Chen, Jinhong Wang, Kaiming Zhuo, Xiaoyun Guo, Kristina Zeljic, Kristina Zeljic, Wenli Li, Wenli Li, Yu Sun, Zheng Wang, Yao Li, Yao Li, Dengtang Liu, Dengtang Liu   +17 more
doaj   +1 more source

Spontaneous dyskinesia in first episode schizophrenia [PDF]

Journal of Neurology, Neurosurgery & Psychiatry, 1997
In the west London prospective study of first episode schizophrenia, the prevalence and nature of abnormal involuntary movements were examined in 27 patients who had never received antipsychotic drugs and 36 who had been treated with such medication. Motor disturbance was assessed with rating scales designed to cover the full range of spontaneous and ...
B K, Puri, T R, Barnes, M J, Chapman, S B, Hutton, E M, Joyce   +4 more
openaire   +2 more sources

History of depression and survival after acute myocardial infarction [PDF]

, 2009
Objective: To compare survival in post-myocardial (MI) participants from the Enhancing Recovery In Coronary Heart Disease (ENRICHD) clinical trial with a first episode of major depression (MD) and those with recurrent MID, which is a risk factor for ...
Blumenthal, J.A., Carney, R.M., Czajkowski, S.M., Davidson, K.W., de Jonge, P., Freedland, K.E., Jaffe, A.S., Steinmeyer, B.   +7 more
core   +4 more sources

Short term pulse frequency fluctuations of OAO 1657-415 from RXTE observations [PDF]

, 2000
We present new X-ray observations of the high mass X-ray binary (HMXRB) pulsar OAO 1657-415, obtained during one orbital period (10.44 days) with the Rossi X-Ray Timing Explorer (RXTE).
Baykal, Altan
core   +3 more sources