Results 181 to 190 of about 248,175 (294)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

First Experience with Hypothermic Oxygenated Perfusion in Human Uteri: Feasibility and Metabolic Characterization. [PDF]

J Clin Med
Sun K, Eshraghi N, Fernandes FW, Satish S, Jiao C, Yildirim FS, Crasta G, Karakaya OF, Takase K, Horie H, Keslar KS, Isaacson D, Baldwin W, Fairchild RL, Hashimoto K, Pita A, Wee A, AlHilli M, Miller C, Eltemamy M, Falcone T, Tzakis A, Richards E, Schlegel A.   +23 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

CO₂ Reactivity but Not CO₂-Induced Orexin/c-Fos Colocalization Differentially Predicts Alcohol-Seeking Behaviour After Extinction and Retrieval-Extinction in Rats. [PDF]

Addict Biol
Raskin M, Olvera M, Smith KA, Cofresí R, Shumake J, Telch MJ, Otto MW, Smits JAJ, Gonzales R, Lee HJ, Monfils MH.   +10 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Teres minor circle and subscapularis lengthening patterns during forward elevation in lateralized reverse total shoulder arthroplasty. [PDF]

JSES Int
Lante E, Blakeney WG, Bauer S.
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Genotype-matched mapping reveals consistent regional flavour signatures and rhizosphere microbial correlates in spring-flush Yunnan large-leaf tea. [PDF]

Food Chem X
Tong J, Li Y, Zhang Y, Zhang P, Wang K, Zou Q, Shen S.   +6 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Osteochondral Allograft Transplantation of the Knee Using a Low-Cost Custom Hybrid Workstation Instrumentation: Technical Note with an Illustrative Case. [PDF]

J Pers Med
Jurković D, Ivandić S, Čengić T, Ćorluka S.   +3 more
europepmc   +1 more source