Results 81 to 90 of about 487,972 (266)

Explicit limit cycles of a family of polynomial differential systems

Electronic Journal of Differential Equations, 2017
We consider the family of polynomial differential systems $$\displaylines{ x' = x+( \alpha y-\beta x) (ax^2-bxy+ay^2) ^{n}, \cr y' = y-( \beta y+\alpha x) (ax^2-bxy+ay^2) ^{n}, }$$ where a, b, $\alpha $, $\beta $ are real constants and n is ...
Rachid Boukoucha
doaj  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Higher order criterion for the nonexistence of formal first integral for nonlinear systems

Electronic Journal of Differential Equations, 2017
The main purpose of this article is to find a criterion for the nonexistence of formal first integrals for nonlinear systems under general resonance. An algorithm illustrates an application to a class of generalized Lokta-Volterra systems.
Zhiguo Xu, Wenlei Li, Shaoyun Shi
doaj  

On the integrability and dynamics of the Hide, Skeldon and Acheson differential system

Electronic Journal of Qualitative Theory of Differential Equations
The family of systems \begin{equation*} \dot{x}= x(y-1)-\beta z,\quad \dot{y}= \alpha (1-x^2)-\kappa y, \quad \dot{z}= x-\lambda z, \end{equation*} where $(x,y,z) \in \mathbb{R}^3$ and $\alpha$, $\beta$, $\kappa$, $\lambda$ are real parameters, was ...
Érika Diz-Pita, Jaume Llibre, M. Victoria Otero-Espinar, Claudia Valls   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

First integral and integral invariant of Birkhoffian system

Chinese Science Bulletin, 2000
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Mei, Fengxiang, Wu, Huibin
openaire   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Finding Liouvillian First Integrals of Rational ODEs of Any Order in Finite Terms

Symmetry, Integrability and Geometry: Methods and Applications, 2006
It is known, due to Mordukhai-Boltovski, Ritt, Prelle, Singer, Christopher and others, that if a given rational ODE has a Liouvillian first integral then the corresponding integrating factor of the ODE must be of a very special form of a product of ...
Yuri N. Kosovtsov
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source