Results 81 to 90 of about 494,012 (266)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Darboux Integrability Of the Biological System

Al-Rafidain Journal of Computer Sciences and Mathematics
In the given paper, we investigate the integrability of a mathematical model of a 3D biological system. Our results show that the system admits a polynomial first integrals for some parameters, an invariant algebraic surface with an exponential factor ...
Zakariya Hashem Ali, Ahmad Muhamad Husien   +1 more
doaj   +1 more source

Polynomial First Integrals of Quadratic Systems

Rocky Mountain Journal of Mathematics, 2001
The paper contains a classification and the topological phase portraits of all quadratic systems having minimal polynomial first integrals of degree at most 4. The authors prove the existence of minimal polynomial first integrals of any degree for quadratic systems and show that such systems having more than three invariant straight lines have no ...
Llibre, Jaume, Zhang, Xiang
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

First Integral Method for Systems of (1+1)-Dimensional Dispersive Long Wave

Walailak Journal of Science and Technology, 2014
The First Integral method (FIM) is applied to solve a dispersive long wave system. In this method the division theorem, as a statement in commutative Algebra has an important role.
Jafar BIAZAR, Mohamad Bagher MEHRLATIFAN
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

A characterization of centres via first integrals

Journal of Differential Equations, 1988
An isolated critical point of a smooth differential system \(x'=f(x)\) in the plane is proved to be a centre iff there exists a local smooth first integral which has the point in question as an isolated minimum and also iff there exists a local invariant measure which is equivalent with the Lebesgue measure and has smooth density.
L. Mazzi, Sabatini, Marco
openaire   +4 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Hyperbolicity, transversality and analytic first integrals

Journal of Differential Equations, 2004
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source