Results 211 to 220 of about 14,782,076 (302)

CAFs‐mediated histone lactylation reprograms cholesterol metabolism in colorectal cancer to drive CD8+ T cell immunosuppression

The Journal of Pathology, EarlyView.
Abstract The progression of colorectal cancer (CRC) is critically regulated by cancer‐associated fibroblasts (CAFs) within the tumor microenvironment (TME), yet the specific molecular mechanisms by which CAFs influence CRC remain unclear. This study reveals the mechanism by which CAFs promote CRC malignant progression and immune suppression through ...
Huachi Li, Jun Hu, Lei Huang, Zihao Wang, Haoran Tao, Feng Cao, Min Xie   +6 more
wiley   +1 more source

Effects of Probiotic Supplementation from Dry-Off Through Early Lactation on Serum Protein Indices and Free Amino Acids in Dairy Cows: A Randomized Field Study. [PDF]

Int J Mol Sci
Marczuk J, Wrześniewska K, Brodzki P, Brodzki A, Sezer K, Tobolski D.   +5 more
europepmc   +1 more source

Population Pharmacokinetics and Transfer of Gabapentin When Used as a Pain Adjunct for Cesarean Deliveries

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 551-560, March 2025.
ABSTRACT Enhanced Recovery After Surgery (ERAS) protocols for cesarean deliveries (CDs) utilize multimodal pain management strategies that often include gabapentin. While gabapentin is excreted in breast milk, its pharmacokinetics in immediately postpartum lactating women are not known. This observational pharmacokinetic study (NCT05099484) enrolled 21
Rebecca Silvola, Aislinn O'Kane, Michael Heathman, Hannah Marotta, Hayley Trussel, Bobbie Ray, Shelley Dowden, Andrea R. Masters, David M. Haas, Sara K. Quinney   +9 more
wiley   +1 more source

Genetic Parameter Estimation and Accuracy of Selection for Milk Production Traits in Romanian Black and White Cattle: A Bayesian Multi-Trait Animal Model Using MCMCglmm. [PDF]

Animals (Basel)
Grosu H, Mărginean GE, Vidu L, Defta N, Enea DN.   +4 more
europepmc   +1 more source

Salvianolic Acid C Protects Against Hepatic Ischemia–Reperfusion Injury via Heat Shock Protein 90α‐Mediated Activation of the Phosphatidylinositol 3‐Kinase/Protein Kinase B Signaling Pathway

Phytotherapy Research, EarlyView.
Salvianolic acid C (SaC) protects against hepatic ischemia–reperfusion injury (HIRI) by upregulating HSP90α and activating the PI3K/AKT pathway, thereby alleviating oxidative stress, inflammation, apoptosis, and necrosis. ABSTRACT Hepatic ischemia–reperfusion injury (HIRI) is a major challenge in liver surgery, and effective pharmacological ...
Pingping Qiao, Alimu Tulahong, Xinlu Xu, Tiemin Jiang, Ruiqing Zhang, Yanze Lin, Zhongdian Yuan, Rexiati Ruze, Yingmei Shao   +8 more
wiley   +1 more source

Stable First- and Last-Entry Behaviour into the Milking Parlour Is Associated with Temperament and Udder Health Indicators in Lacaune Dairy Ewes. [PDF]

Animals (Basel)
Pajor F, Márta K, Sándorová L, Póti P, Egerszegi I, Bodnár Á.   +5 more
europepmc   +1 more source

Bioelectronic Wearable Sensors Produced by Computerized Embroidery Using a Dual Thread Approach

Small, EarlyView.
A dual‐thread embroidered SmartBra integrates silver‐plated and conductive‐polymer (PECOTEX) threads to enable simultaneous cardiac monitoring and open‐circuit potentiometric sensing of potassium and sodium in a breast milk substitute. The wearable platform is fabricated using computerized embroidery, offering a scalable, proof‐of‐concept route toward ...
Taliya Weinstein, Xintong Li, Hasan Kurt, Selin Olenik, Alexander Silva‐Pinto Collins, José Manuel Rodrigueiro Flauzino, Muhammed Adeel, Laura Gonzalez‐Macia, Meral Yüce, Firat Güder   +9 more
wiley   +1 more source

Effects of Dietary Metabolizable Energy and Crude Protein on Postprandial Metabolite Dynamics and Lactation Performance in Dairy Goats. [PDF]

Metabolites
Li X, Wang L, Hu Z, Hou Q, Wang Y, Shen Y, Mu Y, Lin X, Wang Z.   +8 more
europepmc   +1 more source

Comparison of the effects of rectal examination on heart rate and eye temperature in cattle of different parity

Veterinary Record, EarlyView.
Abstract Background Rectal examination is a routine procedure in bovine reproductive management, but its physiological impact may vary depending on the cow's age and parity. Stress responses during such procedures can negatively affect animal welfare and compliance, especially in inexperienced animals.
Atakan Cortu, Orsan Gungor
wiley   +1 more source

Milk-based multi-omics reveals distinct quality signatures associated with Astragalus polysaccharide supplementation in late lactation goats. [PDF]

Food Chem X
Han S, Wang P, Hu Y, Zhang Q, Wan K, Wang X.   +5 more
europepmc   +1 more source