Results 151 to 160 of about 975,233 (311)

First Nations man.

Colour photograph of a close-up shot of a pastel portrait of a First Nations man. He is wearing earrings and a beaded necklace. His hair is in two braids and tied with a red ribbon. Handwritten on verso: painting sold to Weston.
de Grandmaison, Nicholas, 1892-1978
core  

First-in-man Implantation of the XINSORB Bioresorbable Sirolimus-eluting Scaffold in China

Chinese Medical Journal, 2015
Jia-Hui Chen, Yi-Zhe Wu, Li Shen, Feng Zhang, Zhi-Feng Yao, Jia-Sheng Yin, Meng Ji, Qi-Bing Wang, Lei Ge, Ju-Ying Qian, Xi Hu, Jian Xie, Jun-Bo Ge   +12 more
doaj   +1 more source

Incorporation of the National Institute of Health (NIH) sex as a biological variable policy by R01 grant awardees. [PDF]

Commun Med (Lond)
Warden JH, Parangalan M, Welty LJ, Woitowich NC.   +3 more
europepmc   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

First Nations man with red headband.

Colour photograph of a pastel on paper portrait of a First Nations man. The man is wearing a thin red headband around his forehead. His hair is worn loose, except for a section of hair that is worn in a top knot.
de Grandmaison, Nicholas, 1892-1978
core   +1 more source

Distinct roles of central and peripheral vision in rapid scene understanding. [PDF]

J Vis
Johnson BA, Soni AK, Murlidaran S, Beyeler M, Eckstein MP.   +4 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

First Lady Rosalynn Carter with Unknown Man

, 1979
First Lady Rosalynn Carter poses with an unknown man at the opening ceremonies for the Tampa Museum of Art.
Gandy, George Skip, IV
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source