Results 21 to 30 of about 975,233 (311)

Statistical issues in first-in-man studies

, 2007
In March 2006 a first-in-man trial took place using healthy volunteers involving the use of monoclonal antibodies. Within hours the subjects had suffered such adverse effects that they were admitted to intensive care at Northwick Park Hospital.
Bogacka, B., Bird, S., Working Party on Statistical Issues in First-in-Man Studies, Bailey, R., Lachman, P., Amin, D., Senn, S., Colman, P., Garett, A., Grieve, A.   +9 more
core   +1 more source

Visual analysis of interventions and treatments for post-traumatic stress disorder in the military population over the past decade: a study based on the PubMed database

European Journal of Psychotraumatology
Background: Research on PTSD treatment in military populations is expanding rapidly; it’s important to identify key research priorities and emerging trends from a comprehensive perspective.Objective: This study reviewed trends in intervention and ...
Leling Zhu, Haitao Zhu, Wanjun Yang, Wenmo Zhang, Bing Xie, Feifei Wang, Chen Bian   +6 more
doaj   +1 more source

Noninvasive stereotactic radioablation for the treatment of atrial fibrillation: First‐in‐man experience

Journal of Arrhythmia, 2020
Purpose Catheter ablation is an effective therapy for atrial fibrillation (AF). However, risks remain, and improved efficacy is desired. Stereotactic body radiotherapy (SBRT) is a well‐established therapy used to noninvasively treat malignancies and ...
Pierre C. Qian, Jose R. Azpiri, Jose Assad, Eric Noel Gonzales Aceves, Carlos Erick Cardona Ibarra, Cuauhtemoc de laPena, Miguel Hinojosa, Doug Wong, Thomas Fogarty, Patrick Maguire, Alice Jack, Edward A. Gardner, Paul C. Zei   +12 more
doaj   +1 more source

Difference of the size of average crown width first molar and second molar mandible of the Pawon Man with modern man

Padjadjaran Journal of Dentistry, 2012
Introduction: Pawon Man is prehistoric human who was expected life about 9525-5660 BC and have lived in a Cave Pawon located in Mountain Masigit Village, District Cipatat, Bandung Regency.
Taufik Senjaya, Fahmi Oscandar, Lutfi Yondri   +2 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

First-in-Man Large-Field Intravascular Ultrasound-Guided Transcatheter Aortic Valve Replacement

, 2018
First-in-Man Large-Field Intravascular Ultrasound-Guided Transcatheter Aortic Valve ...
Massoud A. Leesar (5051624), Satinder Singh (3833947), Oluseun O. Alli (5051627), James E. Davies (4429165), Diaa Hakim (5051621), Mark F. Sasse (5051618)   +5 more
core   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Two micromechanical models in acoustoelasticity: A comparative study

, 2000
Herein we derive, under the micromechanical model we proposed earlier, Man and Paroni [14], a complete set of formulae for the twelve material constants in the acoustoelastic constitutive equation for orthorhombic aggregates of cubic crystallites.
Paroni, Roberto, Man, Chi-Sing, Roberto Paroni, Chi-Sing Man   +3 more
core   +1 more source

Consummatio gloriae – zapomniany Tomaszowy motywwcielenia Chrystusa w świetle ST II-II, q.2, a.7

Warszawskie Studia Teologiczne, 2019
St. Thomas Aquinas wrote in ST II-II, q.2, a.7., that the first man could get know about Incarnation of Christ in future. The way of knowing of that is experience of marriage, witch is described by St. Poul as „great mystery”, „concerning Christ and the
Piotr Świerczyński
doaj   +1 more source

First-in-Man Simultaneous Aortic and Mitral Valve Transcatheter Implantation Using Patient-Customized Prostheses

JACC: Case Reports, 2021
Valve disease in the presence of porcelain aorta and severe peripheral artery disease challenge physicians in choosing the appropriate therapy. We used a total transcatheter approach, simultaneously implanting a dedicated mitral and aortic valve ...
Hendrik Ruge, MD, Erion Xhepa, MD, PhD, Michael Joner, MD, Christian König, MD, Thomas Ried, MD, Emin Imeri, MD, Ulf Herold, MD, Markus Krane, MD, Ruediger Lange, MD, PhD, Magdalena Erlebach, MD   +9 more
doaj   +1 more source