Results 151 to 160 of about 14,169,713 (306)
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Statistical Problems and Solutions in Onomastic Research: Exemplified by a Comparison of Given Name Distributions in Germany throughout the 20th Century [PDF]
The German Socio Economic Panel Study (SOEP) offers the rare opportunity to look at patterns of given names amongst a representative sample of more than 50,000 people born since 1900.
Gert G. Wagner, Denis Huschka
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Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
You'll Soon Be Marryin' Me; Song-Foxtrot
G majorModeratoWedding time dearie, in the spring Wedding timeMarion" 3Sung by Pat Rooney of "Rooney ...
http://id.loc.gov/authorities/names/nr95039491 +3 more
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How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
G majorAndante moderatoIf I have wounded any soul todayAn Evening Prayer-2(From cover) "Theme Song of The Gospel Radio Singer Edward Mac ...
Gabriel, Chas. H. (Charles Hutchinson), 1856-1932 +3 more
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