Results 51 to 60 of about 33,103,755 (255)

Reliability Analysis of Semiactive Magnetorheological Dampers Subjected to Harmonic Excitations

open access: yesAdvances in Mechanical Engineering, 2013
It has been seen that semiactive magnetorheological (MR) dampers are not sometimes reliable when employed in the building to contract acceleration demand of the stories.
N. Mohajer Rahbari   +2 more
doaj   +1 more source

An Efficient Time-Variant Reliability Analysis Method with Mixed Uncertainties

open access: yesAlgorithms, 2021
In practical engineering, due to the lack of information, it is impossible to accurately determine the distribution of all variables. Therefore, time-variant reliability problems with both random and interval variables may be encountered.
Fangyi Li   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Reliability methods in dynamic system analysis [PDF]

open access: yes, 2013
textStandard techniques used to analyze a system's response with uncertain system parameters or inputs, are generally Importance sampling methods. Sampling methods require a large number of simulation runs before the system output statistics can be ...
Munoz, Brad Ernest
core  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Reliability Analysis of Damaged Beam Spectral Element with Parameter Uncertainties

open access: yesShock and Vibration, 2015
The paper examines the influence of uncertainty parameters on the wave propagation responses at high frequencies for a damaged beam structure in the structural reliability context.
M. R. Machado, J. M. C. Dos Santos
doaj   +1 more source

FIRST OREDR RELIABILITY METHOD OF STRACTURS USINGA IMPRVED HARMONY SEARCH OPTIMIZATION [PDF]

open access: yesمجله مدل سازی در مهندسی, 2017
The first order reliability method (FORM) is widely used to estimate the failure probability of structures. Appropriate evaluation of the reliability index is more important to estimate the failure probability in FORM.
Behrooz Keshtegar
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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