Results 121 to 130 of about 1,447,047 (318)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

First record of the Zitting Cisticola (Cisticola juncidis Rafinesque, 1810) in Hungary. [PDF]

Opuscula Zoologica Instituti Zoosystematici et Oecologici Universitatis Budapestinensis, 2008
On the 18th of July, 2006, one singing male individual of Zitting Cisticola (Cisticola juncidis) was observed at Lake Kolon, Central Hungary. It is the first record of this species in Hungary.
Németh, Á., Vadász, Cs.
doaj  

First record of Ustilago sporoboli-indici in Australia

, 2017
A leaf smut fungus was collected on Sporobolus natalensis (Giant Rat's Tail grass) from two locations in Queensland during early 2017. The fungus was identified as Ustilago sporoboli-indici based on morphological and DNA sequence data.
Vitelli, Joseph S., Chamberlain, A., A. Chamberlain, Riding, Natasha, Shivas, R.G., Tan, Yu Pei, Tan, Y. P., J. S. Vitelli, Shivas, Roger G., Y. P. Tan, N. Riding, Holdom, D. G., Riding, N., D. G. Holdom, Vitelli, J. S., R. G. Shivas, Holdom, David G.   +16 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

On the record properties of integrated time series [PDF]

, 2003
This paper compares the statistical properties of the records from i.i.d. time series with those of time series containing a single unit root. It is shown that there are important differences in both the limiting distributions and the convergence rates ...
Aparicio, Felipe M.
core  

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Effect of admission blood glucose on early mortality in patients with pontine hemorrhage

Scientific Reports
Elevated admission blood glucose (ABG) is increasingly recognized as a prognostic marker in intracerebral hemorrhage, but its specific role in pontine hemorrhage (PH) remains underexplored.
Junqing Ma, Junhong Hao, Lan Xu, Xiaowei Miao, Yanquan Hou, Zujun Song   +5 more
doaj   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Kiwis in the collection: the New Zealand presence in the published record [PDF]

, 2014
This report characterizes the size and scope of the New Zealand presence in the published record, highlights some of its salient characteristics, and describes its diffusion around the world.
Brian Lavoie
core