Results 81 to 90 of about 1,295,641 (268)

Zoropsis spinimana (Araneae: Zoropsidae) neu für Deutschland

open access: yesArachnologische Mitteilungen, 2006
The first two records of Zoropsis spinimana (Dufour, 1820) in Germany are presented together with a further discovery of the species in Central Switzerland.
Hänggi, Ambros, Bolzern, Angelo
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Interactive and joint effects of toxic metals and oxidative balance score on the risk of mortality in adults with NAFLD

open access: yesEcotoxicology and Environmental Safety
Background: High oxidative balance score (OBS) may mitigate inflammation levels and thereby alleviate the adverse health effects induced by toxic metals.
Hua-nan Chen   +6 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Attenuation of microglial aryl hydrocarbon receptor alters astrocyte activation and chronic pain sensitization in aging

open access: yesOpen Life Sciences
This study aims to examine differences in aryl hydrocarbon receptor (AHR) expression between microglia in aged and adult mice and to investigate the impact of microglial AHR attenuation on chronic pain sensitization.
Sun Jia-Xiao   +3 more
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Rural–urban and age differences in association between depression and suicidal attempt: a large retrospective clinical sample study in China

open access: yesBMJ Open
Objectives To assess the association between depression and suicide attempt (SA) by age and region.Design Cross-sectional study.Setting First Affiliated Hospital of Wannan Medical College from January 2021 to January 2022.Participants Hospitalised ...
Yong Xia, Dandan Ge, Zhonghua Zhang
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Walckenaeria simplex neu für Deutschland (Araneae, Linyphiidae)

open access: yesArachnologische Mitteilungen, 2008
The rare money spider Walckenaeria simplex Chyzer, 1894 was found in 2007 near the city of Meißen (Germany) on a rock overlooking the river Elbe. This is the northernmost occurrence of the species. W.
Kielhorn, Karl-Hinrich
doaj   +1 more source

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