Results 41 to 50 of about 1,034,573 (296)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Generative models of 21 cm Epoch of Reionisation lightcones with 3D scattering transforms

Astronomy & Astrophysics
The 21 cm signal from the Epoch of Reionisation (EoR) is observed as a 3D dataset known as a lightcone, consisting of two spatial sky plane axes and a redshift (frequency) axis.
Hothi Ian, Allys Erwan, Semelin Benoit, Meriot Romain   +3 more
doaj   +1 more source

Open questions in the study of population III star formation [PDF]

, 2008
The first stars were key drivers of early cosmic evolution. We review the main physical elements of the current consensus view, positing that the first stars were predominantly very massive.
A. Stacy, Bruhns, Galli, Glover, Goodwin, Goodwin, J. L. Johnson, Norman, P. C. Clark, R. S. Klessen, S. C. O. Glover, Suchkov, Suchkov, T. H. Greif, Tan, Turk, V. Bromm   +16 more
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

A GLIMPSE into the very faint end of the Hβ+[O III]λλ4960,5008 luminosity function at z ∼ 7 – 9 behind Abell S1063

Astronomy & Astrophysics
We used the ultra-deep GLIMPSE JWST/NIRCam survey to constrain the faint end of the [O III]+Hβ luminosity function (LF) down to 1039erg s−1 at z ∼ 7 − 9 behind the lensed Hubble Frontier Field galaxy cluster Abell S1063.
Korber Damien, Chemerynska Iryna, Furtak Lukas J., Atek Hakim, Endsley Ryan, Schaerer Daniel, Chisholm John, Kokorev Vasily, Saldana-Lopez Alberto, Adamo Angela, Muñoz Julian B., Oesch Pascal A., Meyer Romain, Marques-Chaves Rui, Fujimoto Seiji   +14 more
doaj   +1 more source

Comparing the asteroseismic properties of pulsating extremely low-mass pre-white dwarf stars and δ Scuti stars

EPJ Web of Conferences, 2017
We present the first results of a detailed comparison between the pulsation properties of pulsating Extremely Low-Mass pre-white dwarf stars (the pre-ELMV variable stars) and δ Scuti stars.
Arias J.P.Sánchez, Córsico A.H., Romero A.D., Althaus L.G.   +3 more
doaj   +1 more source

ELECTRONIC TEXTBOOK FOR AMATEUR ASTRONOMERS AND STUDENTS "Binary stars and their evolution"

Odessa Astronomical Publications, 2017
Electronic textbook for members and supervisors of the Youth Academy of Sciences; schoolars and teachers; students of the first courses. Total volume of the printed version is 86pp. The textbook is devoted to 100-th Anniversary of Prof.
L. L. Chinarova
doaj   +1 more source

On the radial distribution of stars of different stellar generations in the globular cluster NGC 3201

, 2010
We study the radial distribution of stars of different stellar generations in the globular cluster NGC 3201. From recently published multicolour photometry, a radial dependence of the location of stars on the giant branch was found.
A. Bragaglia, Bragaglia, Carretta, Carretta, Carretta, Carretta, Carretta, Carretta, Cohen, D'Ercole, D'Orazi, Decressin, Decressin, Denisenkov, E. Carretta, Gratton, Gratton, Harris, Kraft, Kravtsov, Kravtsov, Langer, Marino, Norris, Prantzos, R. G. Gratton, S. Lucatello, V. D'Orazi, Ventura, Yong   +29 more
core   +1 more source

The SPHINX public data release

Astronomy & Astrophysics
Context. Low-ionisation state (LIS) metal absorption lines, such as Si II λ1526, are widely used to trace the properties and dynamics of the interstellar medium (ISM) in galaxies.
Mauerhofer Valentin, Blaizot Jérémy, Garel Thibault, Verhamme Anne, Gazagnes Simon, Kerutt Josephine, Michel-Dansac Leo, Parker Kaelee S., Rosdahl Joakim, Saldana-Lopez Alberto, Trebitsch Maxime, Kimm Taysun, Ocvirk Pierre, Teyssier Romain   +13 more
doaj   +1 more source

Combined Nucleosynthetic Yields of Multiple First Stars

, 2016
Modern numerical simulations of the formation of the first stars predict that the first stars formed in multiples. In those cases, the chemical yields of multiple supernova explosions may have contributed to the formation of a next generation star.
Chan, Conrad, Heger, Alexander
core   +1 more source