Results 131 to 140 of about 3,640,448 (271)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Comparison of Irrigation Penetration into the Apical Part of Canals in Hand and Rotary Instrumentations

open access: yesDental Research Journal, 2007
Introduction: The penetration of irrigating solution to the apical one third of canals and removal of debris are dependent on the final size of the instruments and instrumentation techniques used in the canals.
M. Khabiri   +3 more
doaj  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Combined Source-Channel Coding of Images under Power and Bandwidth Constraints

open access: yesEURASIP Journal on Advances in Signal Processing, 2007
This paper proposes a framework for combined source-channel coding for a power and bandwidth constrained noisy channel. The framework is applied to progressive image transmission using constant envelope -ary phase shift key ( -PSK) signaling over an ...
Fossorier Marc   +2 more
doaj  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Bounded and Periodic Solutions of Semilinear Impulsive Periodic System on Banach Spaces

open access: yesFixed Point Theory and Applications, 2008
A class of semilinear impulsive periodic system on Banach spaces is considered. First, we introduce the -periodic PC-mild solution of semilinear impulsive periodic system.
Wei W, Chen Qian, Wang JinRong, Xiang X
doaj  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

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