Results 91 to 100 of about 367,213 (360)
British Journal of Clinical Pharmacology, EarlyView.Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti +9 more
wiley +1 more source
The Pan African Medical Journal, 2017 INTRODUCTION: first trimester pregnancy is defined as twelve weeks after the last menstrual period. Ultrasonography has revolutionized validation and management of first trimester pregnancies.
Felix Uduma Uduma +4 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Tacrolimus monitoring is generally performed in whole blood (WB). Most (>85%) of circulating tacrolimus is bound to red blood cells. During pregnancy, WB monitoring might be suboptimal because of physiological changes including increased plasma volume and decreased haematocrit.
Jildau R. Meinderts +7 more
wiley +1 more source
Zuranolone: A case study in (regulatory) rush to judgement?
British Journal of Clinical Pharmacology, EarlyView.Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove +4 more
wiley +1 more source
Radiology Case ReportsUterine rupture is a serious and potentially life-threatening complication. It is commonly a complication that happens in the third trimester of pregnancy. Its occurrence in early pregnancy is very rare.
Chaymae Faraj +5 more
doaj +1 more source
Safety of Amlodipine in Early Pregnancy
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019 Background Amlodipine is used for the treatment of hypertension, but reports on its use in early pregnancy are limited. Methods and Results In the present study, we recruited 231 women with chronic hypertension, including those who received amlodipine or
Asako Mito +12 more
doaj +1 more source
Responsiveness of emergency obstetric care systems in low- and middle-income countries: a critical review of the "third delay". [PDF]
, 2012 We reviewed the evidence on the duration, causes and effects of delays in providing emergency obstetric care to women attending health facilities (the third delay) in low- and middle-income countries. We performed a critical literature review using terms
Cavallaro, Francesca L +1 more
core +1 more source
Annals of the Child Neurology Society, EarlyView.ABSTRACT Objective Autism spectrum disorder (ASD) affects 1 in 36 individuals in the United States and is characterized by impaired social communication and restrictive/repetitive behaviors. Individuals with tuberous sclerosis complex (TSC) have a high incidence of ASD (40%) and exhibit congenital brain lesions (tubers), offering a unique lesion‐based ...
Wendy Xiao Herman +10 more
wiley +1 more source
The Effect of Prenatal Stress on Birth Weight: Evidence from the al-Aqsa Intifada [PDF]
No previous study has attempted to estimate the effect of intrauterine exposure to armed conflict, a potential source of stress, on pregnancy outcomes. Drawing on data from the 2004 Palestinian Demographic and Health Survey, we examine the relationship ...
Daniel I. Rees, Hani Mansour
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Screening for Down's syndrome: effects, safety, and cost effectiveness of first and second trimester strategies commentary: rasults may not be widely applicable authors' response [PDF]
, 2001 Objective: To compare the effects, safety, and cost effectiveness of antenatal screening strategies for Down's syndrome. Design: Analysis of incremental cost effectiveness. Setting: United Kingdom.
Ades, A.E. +6 more
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