Results 91 to 100 of about 234,929 (313)

Medical-scientific evidence of fetal pain in the first trimester of pregnancy

Revista Mexicana de Investigación Médica
It has been argued that embryos of fewer than 12 weeks of gestation do not feel pain; however, in this review where an analysis of the existing literature was carried out, different authors mention that fetal pain is difficult to assess because the main ...
José Manuel Madrazo Cabo, Paulina Chagollán Gudiño, Gabriela Sánchez Machorro, David Blumenkron Marroquín, Gonzalo Joel Uribe Mayén, Martha Margarita Luz Tarasco Michel   +5 more
doaj   +1 more source

Aneuploidy screening in the first trimester [PDF]

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, 2007
AbstractThis article reviews the performance of first trimester screening for chromosomal anomalies using various combinations of ultrasound and maternal serum biochemical modalities. Detection rates in excess of 90% can be routinely achieved for Trisomy 21, Trisomy 13, Trisomy 18 using a combination of fetal nuchal translucency (NT) thickness and ...
openaire   +2 more sources

First Trimester Ultrasonographic Diagnosis of Unruptured Rudimentary Horn Pregnancies in Two Cases

, 2016
Pregnancy in a woman with unicornuate uterus with non-communicating uterine horn is a considerably rare condition with an incidence of one in 100.000 cases. Fertilization occurs by transperitoneal migration of sperm and, uterine rupture is a considerably
Nazife Kartal, Metin Altay, Rıza Dur, Füsun Bocutoğlu, Derya Akdağ Cırık, Metin Kaplan   +5 more
core   +1 more source

Physiologically‐based pharmacokinetic modelling of uridine 5′‐diphosphoglucorosultransferase (UGT) substrate drugs in pregnant women

British Journal of Clinical Pharmacology, EarlyView.
Aims While pregnancy‐related changes in phase I enzyme activity are well‐documented, less is known about the impact on phase II enzymes. This study aimed to test the hypothesis that changes in the pharmacokinetics (PK) of uridine 5′‐diphosphoglucuronosyltransferase (UGT) substrates during pregnancy result from altered enzyme expression or activity ...
William Saffaf, Ymke van der Velde, Paul R. V. Malik, Jelmer R. Prins, Sanne J. Gordijn, Daan J. Touw, Paola Mian   +6 more
wiley   +1 more source

First Trimester Miscarriage. Invisible Mourning

Musas
AIM. The objective of the study was to describe the experience during hospital care of first trimester pregnant women admitted for spontaneous abortion and their experiences after post-abortion discharge.
Camila Alarcón-Catalán, Sofía Romero-Marchant, Marisa Villagran-Becerra, Paula Cabello-Hidalgo, Barbara Padilla-González   +4 more
doaj   +1 more source

Pregnancy‐related effect on elexacaftor, tezacaftor and ivacaftor pharmacokinetics in women with cystic fibrosis

British Journal of Clinical Pharmacology, EarlyView.
Aim The number of pregnancies among women with cystic fibrosis (wwCF) has steadily increased over the past decade. However, the pharmacokinetics (PK) of elexacaftor–tezacaftor–ivacaftor (ETI) during gestation remains uncharacterized, despite its widespread use in this population.
Paulette Magnas, Naim Bouazza, Frantz Foissac, Saïk Urien, Léo Froelicher‐Bournaud, Gabrielle Lui, Victoria Guillemart, Nicolas Carlier, Jennifer Da Silva, Johanna Fesenbeckh, Reem Kanaan, Isabelle Honoré, Clémence Martin, Jean‐Marc Treluyer, Vassilis Tsatsaris, Pierre‐Régis Burgel, Sihem Benaboud   +16 more
wiley   +1 more source

Partial trisomy 9: prenatal diagnosis and recurrence within same family

Clinical Case Reports, 2017
Key Clinical Message Trisomy 9 can be suspected and confirmed in the prenatal period since the 11–13.6 weeks of screening. In cases of partial trisomy 9, the diagnosis is important especially to counseling the couple due to the increased likelihood of ...
Jana López‐Félix, Leticia Flores‐Gallegos, Luz Garduño‐Zarazúa, Teresa Leis‐Márquez, Luz Juárez‐García, Ricardo Meléndez‐Hernández, Ernesto Castelazo‐Morales, Dora Mayén‐Molina   +7 more
doaj   +1 more source

Safety of Amlodipine in Early Pregnancy

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Amlodipine is used for the treatment of hypertension, but reports on its use in early pregnancy are limited. Methods and Results In the present study, we recruited 231 women with chronic hypertension, including those who received amlodipine or
Asako Mito, Atsuko Murashima, Yoshinao Wada, Mai Miyasato‐Isoda, Chizuko A. Kamiya, Masako Waguri, Jun Yoshimatsu, Naho Yakuwa, Omi Watanabe, Tomo Suzuki, Naoko Arata, Masashi Mikami, Shinya Ito   +12 more
doaj   +1 more source

Government Subsidies for Industrial Symbiosis: Is It Always Worth It? Assessing Effectiveness and Efficiency Through Agent‐Based Modeling

Business Strategy and the Environment, EarlyView.
ABSTRACT Policy intervention can be a driver for industrial symbiosis (IS). However, given the wide variety of policy instruments available, policymakers should be guided in the policy design process to ensure that their intervention is effective and efficient. In this paper, we propose an agent‐based (AB) model intended to assess the effectiveness and
Melissa Mollica, Alberto Nastasi, Luca Fraccascia   +2 more
wiley   +1 more source

Effect of Late Second to Early Third Trimester of Pregnancy on the Activity of Renal Organic Anion Transporters (OAT1 and OAT3): A Biomarker Study

Clinical Pharmacology &Therapeutics, EarlyView.
Pregnant individuals take drugs throughout pregnancy and many of these drugs (e.g., antivirals, antibiotics) are eliminated by renal organic anion transporters (OAT) 1 and OAT3. In vivo studies with OAT1/3 substrate drugs suggest that pregnancy increases renal OAT1/3 activities by 1.5‐ to 1.8‐fold.
Aarzoo Thakur, Jashvant D. Unadkat, Emily E. Fay, Nina Isoherranen, Mary F. Hebert   +4 more
wiley   +1 more source