Results 231 to 240 of about 351,972 (313)

Attitudes Toward Prenatal Interventions in the Fanconi Anemia Community

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective In‐utero cell and gene therapies may offer prenatal treatment options for inherited diseases. Preclinical data suggests in‐utero (IU) hematopoietic stem cell transplantation (HSCT) could prevent Fanconi anemia (FA) related bone marrow failure without genotoxic conditioning or immune suppression.
Tony Lum, Catherine Lee, Tippi MacKenzie, Billie Lianoglou, Agnieszka Czechowicz   +4 more
wiley   +1 more source

Reference charts for first-trimester placental three-dimensional fractional moving blood volume derived using OxNNet. [PDF]

Ultrasound Obstet Gynecol
Mathewlynn S, Starck LN, Yin Y, Soltaninejad M, Swinburne M, Nicolaides KH, Syngelaki A, Contreras AG, Bigiotti S, Woess EM, Gerry S, Collins S.   +11 more
europepmc   +1 more source

“The Way We Do Things is Unsustainable”—Exploring Symptoms of Burnout Among Healthcare Professionals in Prenatal Genomics

Prenatal Diagnosis, EarlyView.
ABSTRACT Objectives This research explored a cross‐country comparison of qualitative and quantitative data assessing the experiences of prenatal genomic healthcare professionals (HCP) in Australia and the Netherlands. Method The interview script included open‐ended questions on work experience, validated scales on compassion fatigue and stress, and ...
Maayke de Koning, Sarah Long, Marit de Vries, Holly Evans, Lauren Kelada, Monique Haak, Gemma Fernihough, Gijs Santen, Manon Suerink, Tony Roscioli   +9 more
wiley   +1 more source

Clinical audit for first-trimester ultrasound screening: a single center experience. [PDF]

Front Med (Lausanne)
Wu X, Zhang Y, Meng H, Ouyang Y, Xu Z, Dai Q, Zhang P.   +6 more
europepmc   +1 more source

Prenatal Detection of Fetal Abdominal Cysts: Can We Reassure Future Parents?

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This study aimed to evaluate the perinatal outcome of fetal abdominal cysts based on the timing of prenatal diagnosis and identify prenatal characteristics associated with postnatal surgical intervention. Methods Fetuses with prenatally detected isolated abdominal cysts referred between January 2007 and December 2022 were included ...
H. Heinrich, E. W. M. Grijseels, R. Bakx, R. R. Gorter, E. van den Boogaard, E. van Leeuwen, A. Elvan‐Taşpınar, I. H. Linskens, E. Pajkrt   +8 more
wiley   +1 more source

NONO‐Related Syndromic X‐Linked Developmental Disability 34: Further Clinical and Molecular Delineation in a Prenatal Cohort

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To characterize the prenatal sonographic features across different trimesters and genomic spectrum of NONO‐related X‐linked intellectual developmental disorder. Method We analyzed two fetuses presenting with corpus callosum agenesis and rare cardiac anomalies using genome sequencing and exome sequencing.
Yilin Zhao, Gang Zou, Mengmeng Shi, Kwok Ming Law, So Ling Lau, Meng Meng, Yuen Ha Ting, Chiu Yee Liona Poon, Zirui Dong, Matthew Hoi Kin Chau, Tak Yeung Leung, Kwong Wai Choy, Xinwen Zhang, Ye Cao   +13 more
wiley   +1 more source

Deliberate use of mycophenolate mofetil in pregnant patients with lupus after the first trimester. [PDF]

Lupus Sci Med
Abida H, Tamirou F, Debiève F, Houssiau FA.   +3 more
europepmc   +1 more source

Clinical Grading of Artificial Intelligence‐Based 3D Fetal Brain Segmentations: A Cross‐Vendor Evaluation of Deep Learning in Fetal Neuroimaging

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To evaluate the performance of automated (sub)cortical fetal brain segmentation methods on a novel 3D ultrasound dataset acquired from a different vendor, and to introduce a clinician‐focused visual evaluation framework complementary to the widely used Dice Similarity Coefficient (DSC).
Moska Aliasi, Linde S. Hesse, Madeleine K. Wyburd, Maartje C. Snoep, Renee M. Smit, Ana I. L. Namburete, Monique C. Haak   +6 more
wiley   +1 more source

Efficacy and Safety of Letrozole, Misoprostol and Their Combination in First Trimester Missed Miscarriage: <i>A randomised clinical trial</i>. [PDF]

Sultan Qaboos Univ Med J
Fikry Yousef M, Abdelfatah Sheeba M, Saad Amin Mohamed H, Adel Abdelmonem Salama A, Hassan A, Taghian M, Mostafa Hassan Ali M, Ragab Ebrahim Ragab A, Hassan A, Alasmer A, Ramadan Mohamed M.   +10 more
europepmc   +1 more source

Diagnostic Yield of Sequencing for Prenatal Diagnosis of Fetal Structural Anomalies: An Updated Systematic Review

Prenatal Diagnosis, EarlyView.
ABSTRACT The clinical utility of sequencing in prenatal diagnosis is known, but diagnostic yield varies widely depending on clinical indication. Here we update an earlier systematic review reporting the diagnostic yield of prenatal sequencing in structurally abnormal fetuses, with particular focus on factors affecting diagnostic yield.
Karen Mei Xian Lim, Alexander Gibbs, Elizabeth Scotchman, Graeme Smith, Lyn S. Chitty, Natalie J. Chandler   +5 more
wiley   +1 more source