Results 51 to 60 of about 2,260,299 (337)

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

“The moaning of the world” and the “words that bring me peace”: Modernism and the First World War [PDF]

open access: yes, 2012
This chapter takes its place in a huge new project on twentieth-century British and American war literature. It focuses on technology and sense perception in First World War writing in its account of the formal and contextual relationships between ...
Haslam, Sara
core  

Novel and unscrutinized immune entities of the zebrafish gut

open access: yesFEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil   +5 more
wiley   +1 more source

Developing Deadly Skies [PDF]

open access: yes, 2016
The Canadian War Museum’s exhibition Deadly Skies – Air War, 1914-1918 examines the first air war from the perspective of nine international participants representing Canada, the United States, France, Great Britain, and Germany.
Maker, John
core   +1 more source

Britishness and commemoration: National memorials to the First World War in Britain and Ireland [PDF]

open access: yes, 2013
The 1917 call for a national memorial to the First World War led to the establishment of the Imperial War Museum in London. It also inspired Scottish, Welsh and Irish national memorials.
Macleod, Jenny
core   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Thomas Crombez, Luk van den Dries (eds.), Mass Theatre in Interwar Europe: Flanders and the Netherlands in an International Perspective

open access: yesBMGN: Low Countries Historical Review, 2015
Thomas Crombez, Luk van den Dries (eds.), Mass Theatre in Interwar Europe: Flanders and the Netherlands in an International Perspective (Leuven: Universitaire pers Leuven, 2014, 164 pp., ISBN 978 90 5867 992 5).
Maartje Abbenhuis
doaj   +1 more source

The First World Oil War (Book Review) by Timothy C. Winegard [PDF]

open access: yes, 2018
Review of The First World Oil War by Timothy C ...
Williamson, Corbin
core   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Bodies of War: Disabilities and Heroism in the First World War

open access: yesJournal of Lusophone Studies, 2018
In the present article, I analyze discourses of masculinity and the male body associated with Portugal’s involvement in World War I. I examine these from three perspectives: the national military body; medical and political discussion of disabled bodies;
Rhian Atkin
doaj   +1 more source

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