Results 61 to 70 of about 19,763,523 (261)

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Cost‐utility analysis of nusinersen–risdiplam switch in patients with spinal muscular atrophy in Croatia: A discrete event simulation model

British Journal of Clinical Pharmacology, EarlyView.
Introduction In recent years, the treatment of spinal muscular atrophy (SMA), a rare disease, has significantly progressed, improving patients' survival and overall quality of life. However, current SMA treatments are expensive, and some (nusinersen) are very inconvenient for patients.
Andrej Belančić, Ivana Stević, Elvira Meni Maria Gkrinia, Dinko Vitezić, Slobodan Janković   +4 more
wiley   +1 more source

Extremal values on Zagreb indices of trees with given distance k-domination number

Journal of Inequalities and Applications, 2018
Let G = ( V ( G ) , E ( G ) ) $G=(V(G),E(G))$ be a graph. A set D ⊆ V ( G ) $D\subseteq V(G)$ is a distance k-dominating set of G if for every vertex u ∈ V ( G ) ∖ D $u\in V(G)\setminus D$ , d G ( u , v ) ≤ k $d_{G}(u,v)\leq k$ for some vertex v ∈ D $v ...
Lidan Pei, Xiangfeng Pan
doaj   +1 more source

The First Zagreb Index, The Wiener Index, and The Gutman Index of The Power of Dihedral Group

CAUCHY: Jurnal Matematika Murni dan Aplikasi, 2023
Research on graphs combined with groups is an interesting topic in the field of combinatoric algebra where graphs are used to represent a group. One type of graph representation of a group is a power graph. A power graph of the group G is defined as a graph whose vertex set is all elements of G and two distinct vertices a and b are adjacent if and only
Evi Yuniartika Asmarani, Sahin Two Lestari, Dara Purnamasari, Abdul Gazir Syarifudin, Salwa Salwa, I Gede Adhitya Wisnu Wardhana   +5 more
openaire   +2 more sources

Economic evaluations of antiobesity medications: A systematic literature review

British Journal of Clinical Pharmacology, EarlyView.
The global prevalence of obesity is rising rapidly. With several antiobesity medications approved and many more in development, understanding their economic value is increasingly important. This study reviews full economic evaluations of approved antiobesity medications to assess cost‐effectiveness and inform reimbursement and access decisions.
Martina Jurković, Almir Fajkić, Andrea Katrin Faour, Mirna Momčilović, Petra Turčić, Andrej Belančić   +5 more
wiley   +1 more source

The Topological Indices of Coprime Graph for Integer Module Group

Jurnal Diferensial
This study delves into the fascinating realm of coprime graphs within the integer modulo group, revealing a fundamental property where these graphs manifest as star graphs when the order corresponds to a prime power.
Abdurahim Abdurahim, Zata Yumni Awanis, Bulqis Nebulla Syechah, Syaharuddin Syaharuddin   +3 more
doaj   +1 more source

A lower bound for the first Zagreb index and its application [PDF]

, 2015
For a graph G, the first Zagreb index is defined as the sum of the squares of the vertices degrees. By investigating the connection between the first Zagreb index and the first three coefficients of the Laplacian characteristic polynomial, we give a ...
Wang, Jian Feng, BELARDO, Francesco
core  

Towards appropriate guidance for the ethical challenges of environmentally sustainable prescribing

British Journal of Clinical Pharmacology, EarlyView.
The environmental impact of medicines poses a significant threat to planetary and public health, making it essential to integrate environmental sustainability into prescribing practices. While the most effective measures to reduce environmental impact, such as reducing unnecessary prescriptions and medication waste, are consistent with appropriate ...
Joost D. Piët, Steven R. Kraaijeveld, Erik M. Donker, Milan C. Richir, Caroline T. A. Moermond, Amy Booth, SanYuMay Tun, Thijs H. Oude Munnink, Patricia M. L. A. van den Bemt, Lorena Dima, Ben J. A. Janssen, Mathilde Jalving, Tomás Mauro van Emden, Fabrizio de Ponti, Robert Likic, João Costa, Marc Labriffe, Charlotte L. Bekker, Carlotta Lunghi, Elisabetta Poluzzi, Michiel A. van Agtmael, Yolande Voskes, Jelle Tichelaar   +22 more
wiley   +1 more source

Computing Topological Indices and Polynomials for Line Graphs

Mathematics, 2018
A topological index is a number related to the atomic index that allows quantitative structure–action/property/toxicity connections. All the more vital topological indices correspond to certain physico-concoction properties like breaking point ...
Shahid Imran, Muhammad Kamran Siddiqui, Muhammad Imran, Muhammad Faisal Nadeem   +3 more
doaj   +1 more source

Zagreb Connection Number Index of Nanotubes and Regular Hexagonal Lattice

Open Chemistry, 2019
Topological indices are the fixed numbers associated with the graphs. In recent years, mathematicians used indices to check the pharmacology characteristics and molecular behavior of medicines.
Ye Ansheng, Qureshi Muhammad Imran, Fahad Asfand, Aslam Adnan, Jamil Muhammad Kamran, Zafar Asim, Irfan Rida   +6 more
doaj   +1 more source