Results 51 to 60 of about 24,476 (263)

ASSESSING FISCAL CAPACITY THROUGH STAKEHOLDER SATISFACTION IN PUBLIC FUNDING

Север и рынок: формирование экономического порядка
Amid the current crisis, the growing influence of negative factors threatens the fiscal capacity of regions, potentially undermining budgetary policy and the effective realization of individual, public, and national interests.
Tatiana I. Barasheva
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

A New EU Economic Governance and Fiscal Framework: What Role for the National Independent Fiscal Institutions (IFIs)? [PDF]

Romanian Journal of European Affairs, 2023
The European Commission’s communication on orientations for a reform of the European Union’s economic governance framework asks the European Fiscal Board (EFB) and national Independent Fiscal Institutions (IFIs) to play a more significant role in it ...
Daniel Dăianu
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Improving the Assessment of Regional Tax Capacity by Selected Types of Taxes [PDF]

Финансовый журнал
Sub-federal authorities have the power to administer transportation tax, gambling tax, local taxes and taxes on total income, including setting rates, providing benefits or determining the tax base, which makes these taxes an important instrument of sub ...
Igor Yu. Arlashkin
doaj   +1 more source

ANALISIS KEMAMPUAN FISKAL PEMERINTAH KABUPATEN DAN KOTA DI JAWA TIMUR DALAM TRANSPARANSI DI WEBSITE

Jurnal Akademi Akuntansi, 2020
This research aims to analyze the relationship between the fiscal capacity of district and city governments in East Java Province with uploading on the website.
Setu Setyawan
doaj   +1 more source

Fiscal institutions and the development of fiscal capacity: The case of fiscal rules

, 2023
The development of fiscal capacity is widely acknowledged as an important pillar for strong state-building. However, the level of fiscal capacity remains structurally low mostly in developing countries due to a number of factors, including the lack of institutions driving governments to channel public resources to public interests or the substitution ...
Apeti, Ablam Estel, Combes, Jean-Louis, Minea, Alexandru   +2 more
openaire   +1 more source

Is There a Fiscal Resource Curse? Resource Rents, Fiscal Capacity and Political Institutions [PDF]

SSRN Electronic Journal, 2018
While several studies have focused on the effect of natural resources on economic development, less attention has been paid to their effects on other development outcomes. We contribute to this literature by studying the impact of resource rents on fiscal capacity, i.e., the ability of states to raise revenues from broad tax bases.
Masi, Tania, Savoia, Antonio; id_orcid 0000-0003-0639-9705, Sen, Kunal   +2 more
openaire   +3 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source