Results 121 to 130 of about 796,882 (310)

Near‐Infrared Fluorescent PROTAC Enables Theranostic Imaging and Selective Tau Degradation in Alzheimer's Disease

Advanced Science, EarlyView.
Here, we report a novel NIR fluorescent PROTAC platform that enables real‐time imaging and targeted degradation of Alzheimer's p‐Tau. Our lead compound effectively clears p‐Tau, reduces APP/Aβ, and alleviates cognitive deficits in AD mice. This work demonstrates a theranostic strategy for visualizing degradation and developing next‐generation AD ...
Ziwei Ren, Qian Yue, Ning Gao, Qiu‐Lian Hao, Yan Huo, Chuchu Li, Xinyue Leng, Lu‐Lu Sun, Maggie Pui Man Hoi, Hai‐Hao Han, Mingliang Ma, Xu‐Wen Li   +11 more
wiley   +1 more source

The relationship between fiscal deficit and trade deficit in Vietnam over the period 1990 –2014

Tạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kinh tế và Quản trị kinh doanh, 2020
The relationship between fiscal deficit and trade deficit has long been an interesting issue in many countries, especially in such a developing country like Vietnam.
Trịnh Thị Liên, Trần Văn Hùng
doaj  

The Role of Independent Fiscal Policy Institutions [PDF]

The paper analyses how independent fiscal watchdogs (fiscal policy councils) can strengthen the incentives for fiscal discipline. By increasing fiscal transparency they can raise the awareness of the long-run costs of current deficits and increase the ...
Lars Calmfors
core  

Proteogenomic Profiling of Idiopathic Pulmonary Arterial Hypertension Identifies Sex‐Differential Proteins and Candidate Therapeutic Targets

Advanced Science, EarlyView.
An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin, Yangchang Zhang, Yang Pu, Duanke Liu, Tao Lei, Kai Ma, Qiyu He, Zheng Dou, Yuze Liu, Dengyuan Liu, Yinge He, Yanshang Wang, Xiaojiao Zheng, Yanbing Ma, Jianrong Zhou, Weiding Zhai, Binbin Su, Li Chen, Shoujun Li   +18 more
wiley   +1 more source

Debt-deficit dynamics in India and macroeconomic effects: A structural approach [PDF]

The structural approach adopted in this paper aims to trace out the evolution of public debt and deficits over a medium term horizon and its dynamic interaction with other key macroeconomic variables such as interest rate, inflation, trade gap and output.
Kannan, R, Singh, Bhupal
core  

Surface‐Functionalized MXene for Enhanced Photocatalytic CO2 Reduction

Advanced Energy Materials, EarlyView.
Poly(catechol/p‐cresol)‐functionalized MXene (f‐MXene) enhances oxidation stability while preserving conductivity, enabling efficient interfacial electron transfer in a Cu/f‐MXene/reduced TiO2 photocatalyst. Strong Cu–f‐MXene synergy promotes CO2 activation and selective CH4 production, achieving a CH4 yield of 18.1 µmol g−1 (>200 × vs.
Dongyun Kim, Young Ho Park, Dong Gyu Lee, Kyuseok Lee, Junho Lee, Chaelin Shin, Jaeyoung Kim, B. Yamunasree, Soomin Han, Eunhee Gong, Hyeonjong Jeong, Min Gyu Kim, Chang‐Hee Cho, Seung Jun Lee, Soorathep Kheawhom, G. Murali, Tae Kyung Lee, Insik In, Su‐Il In   +18 more
wiley   +1 more source

Fiscal Sustainability in Iran A Markov-Switching Fiscal Regime Change and Time-Varying Parameter Models Approach [PDF]

پژوهشهای اقتصادی
Aim and Introduction A balanced government budget plays a decisive role in the stability of the macroeconomics, and the continuous budget deficit puts the stability of the economy at risk.
Hossein Aghilifar, Khosrow Piraei, Hashem Zare, Mehrzad Ebrahimi   +3 more
doaj  

Fiscal Policy Issues for India after the Global Financial Crisis (2008-2010) [PDF]

The need for fiscal consolidation and sustainability is one of the key macroeconomic issues confronting Indian economy. This paper attempts to understand India's current fiscal situation, its likely future development, and its impact on the economy in ...
Soumya, Alamuru, Kumar, Rajiv
core  

How Video‐Based Information Affects Farmers' Willingness to Pay for Drone Services

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Professional service for digital technology like agricultural drones lowers transaction costs and scope thresholds for smallholders. Meanwhile, perceptual adoption barriers remain underexplored. We conduct a two‐stage choice experiment with a randomized video‐based information treatment among 384 Chinese crop farmers to measure its effect on ...
Hua Zhang, Lena Kuhn, Hang Xiong, Zhanli Sun, Thomas Glauben   +4 more
wiley   +1 more source

O debate sobre a redução do déficit fiscal no Brasil: uma crítica pós-keynesiana

Nova Economia, 2011
O artigo analisa o debate sobre a redução do déficit fiscal brasileiro com base em uma perspectiva pós-keynesiana. Após resumir as conclusões das controvérsias sobre o pa-pel da moeda e do Estado que constituem a base dos desacordos quanto à política ...
Mariana de Lourdes Moreira Lopes, Maria de Lourdes Rollemberg Mollo   +1 more
doaj