Results 91 to 100 of about 2,432,054 (308)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

The Effects of Fiscal Institutions on Public Finance: A Survey of the Empirical Evidence [PDF]

open access: yes
This paper surveys the empirical research on fiscal institutions of the last three decades. The main results are: (i) Constitutional or statutory fiscal limitations have in most cases proved to be effective in cutting down public expenditure, revenue ...
Gebhard Kirchgässner
core  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

National parliaments fighting back? Institutional engineering as a successful means to become active actors in EU affairs

open access: yesPerspectives on Federalism, 2016
The European integration process has long been characterised by the predominance of national executive powers. National parliaments were recognised as European actors after several decades only, in the Maastricht Treaty first and to an even larger extent
Fromage Diane
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

The Activity of Independent Fiscal Institutions in the Republic of Poland and the Czech Republic – A Comparative Legal Study

open access: yesPrawo Budżetowe Państwa i Samorządu
Pursuant to the Act of 21 November 2024 on the Fiscal Council, which was adopted to implement the provisions of Council Directive 2011/85/EU of 8 November 2011 on requirements for budgetary frameworks of the Member States, an independent fiscal ...
Michał Zawada, Miłosz Kwiatkowski
doaj   +1 more source

The Macroeconomics of Loss of Fulltime Student Status or the Fiscal Consequences of Passing or Not Passing an Exam [PDF]

open access: yesFinancial Theory and Practice, 2009
This article is the first systematic attempt at an overview of the extent of fiscal and non-fiscal support to students in Croatia, taking University of Split as an example.
Petar Filipić
doaj  

Fiscal institutions and the development of fiscal capacity: The case of fiscal rules

open access: yes, 2023
The development of fiscal capacity is widely acknowledged as an important pillar for strong state-building. However, the level of fiscal capacity remains structurally low mostly in developing countries due to a number of factors, including the lack of institutions driving governments to channel public resources to public interests or the substitution ...
Apeti, Ablam Estel   +2 more
openaire   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

The role of fiscal rules and institutions in shaping budgetary outcomes [PDF]

open access: yes
The Workshop "The role of fiscal rules and institutions in shaping budgetary outcomes" organized by the Directorate-General for Economic and Financial affairs of the European Commission on 24 November 2006 in Brussels aimed at enriching the debate on the
S. Deroose   +3 more
core  

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