Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang +8 more
wiley +1 more source
Medical Debt, Credit Card Debt, and Other Financial Debt Among Veterans Who Receive Homeless Assistance in the Veterans Affairs Healthcare System. [PDF]
Beydoun HA, Szymkowiak D, Tsai J.
europepmc +1 more source
ABSTRACT Current clinical approaches for knee cartilage repair are often limited by hypertrophy and fibrosis in the regenerated tissues. A decellularized tissue‐engineered hyaline cartilage graft (dLhCG), composed of a type II collagen‐based extracellular matrix, has been developed to overcome this limitation.
Zhen Zhang +16 more
wiley +1 more source
Fiscal Incentives and Health Risk Protection: How Central-Local Fiscal Relations Shape Rural Households' Medical Burden in China. [PDF]
Zhang Y, Liu P, Li T, Zhao L.
europepmc +1 more source
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He +10 more
wiley +1 more source
The political economy of health reforms and out-of-pocket spending in Türkiye: evidence from household microdata, 2014-2023. [PDF]
Cece S, Pınar A, Öztürk L, Şenay D.
europepmc +1 more source
Superatom Distortion Induces Triferroicity and Spin Splitting in Two‐Dimensional Antiferromagnets
The incorporation of superatoms into a 2D square lattice induces symmetry breaking, thereby enabling concurrent coupling among magnetism, ferroelectricity, and ferroelasticity. This strategy achieves triferroic behavior—characterized by spin‐split antiferromagnetic ground states—and offers a viable pathway toward energy‐efficient spintronic devices ...
Zhen Gao +6 more
wiley +1 more source
The feasibility of social impact bonds in financing tertiary health care quality: qualitative stakeholders' perspectives in Kenya. [PDF]
Karino E, Ndegwa J, Were V.
europepmc +1 more source
Legal Financial Obligations: An Understudied Public Health Exposure. [PDF]
Lindenfeld Z, Rouhani S.
europepmc +1 more source
Legal and systemic implications of the 2023 Polish act on certain medical professions-regulation, workforce requirements, healthcare system impact. [PDF]
Pacian JA, Piekut MJ.
europepmc +1 more source

