Results 41 to 50 of about 13,945 (259)
Mali Sürdürülebilirlik Analiz Yöntemlerinde Yaşanan Gelişmelere Teorik Bir Bakış
International Journal of Public Finance, 2022 Günümüzde iktisadi faaliyetlerin yapısı ülkelerin maliye politikasında karşı karşıya oldukları risklerin çeşitlenmesine yol açmıştır. Nitekim dış ticaretten finansa ülkeler arası ekonomik ilişkilerin çok daha yoğun bir hale gelmesi ekonomileri ...
Semih Şen
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
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Potential Output, EU Fiscal Surveillance and the COVID-19 Shock
Intereconomics, 2020 This paper discusses how the technical foundations of the EU’s fiscal rules constrain the fiscal space in EU countries in the context of the COVID-19 pandemic.
Philipp Heimberger
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Australia's Fiscal Space: The Role of Public Investment
Australian Economic Review, 2022 AbstractHow large is Australia's fiscal space? Blanchard (2019) shows that as long as the real interest rate is below the real growth rate , a government can sustain a positive primary deficit with a constant (or even declining) ratio of public debt to GDP.
Domínguez, Begoña, Quiggin, John
openaire +3 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Macroeconomic Vulnerabilities and Exogenous Shocks in Romania in the European Context [PDF]
Annals of Dunarea de Jos University. Fascicle I : Economics and Applied InformaticsIn the context of successive crises—from the 2008 financial collapse to the COVID-19 pandemic, followed by post-2022 inflationary pressures and geopolitical tensions—Romania’s macroeconomic stability has been increasingly tested.
Andreea Mogda
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Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
E-ManagementUnder the circumstances of the dynamic geopolitical situation, it is becoming increasingly important to develop an effective methodology for assessing fiscal space. Fiscal space formation depends on a number of key factors, including economic development
M. E. Kosov
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