Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Putative fishery-induced changes in biomass and population size structures of demersal deep-sea fishes in ICES Sub-area VII, Northeast Atlantic Ocean [PDF]
, 2012 This work was supported by a series of NERC grants to the principal investigators including NE/C512961/1. The results of the early joint SAMS and IOS surveys were digitized with support from EU MAST Contract MAS2-CT920033 1993–1995, and data analyses was
Bailey, D. M. +5 more
core +4 more sources
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Biophysical factors affecting the distribution of demersal fish around the head of a Submarine Canyon off the Bonney Coast, South Australia. [PDF]
PLoS ONE, 2012 We sampled the demersal fish community of the Bonney Canyon, South Australia at depths (100-1,500 m) and locations that are poorly known. Seventy-eight species of demersal fish were obtained from 12 depth-stratified trawls along, and to either side, of ...
David R Currie +3 more
doaj +1 more source
Fish assemblages found in tidal-creek and seagrass habitats in the Suwannee River estuary [PDF]
, 2006 Fish assemblages were investigated in tidal-creek and seagrass habitats in the Suwannee River estuary, Florida. A total of 91,571 fish representing 43 families were collected in monthly seine samples from January 1997 to December 1999.
Dehaven, Mark, Tuckey, Troy D.
core +1 more source
Diet uniformity at an early farming community in northwest Anatolia (Turkey) : carbon and nitrogen isotope studies of bone collagen at Aktopraklik [PDF]
, 2017 Aktopraklık is a settlement site composed of three areas (A–C) in the Marmara region of northwest Anatolia, with phases of occupation that date to the Late Neolithic and Early Chalcolithic periods, mid-seventh to mid-sixth millennium bc (ca.
Alpaslan-Roodenberg, Songül +5 more
core +1 more source
Novel Ecosystems: Altering Fish Assemblages in Warming Waters [PDF]
Current Biology, 2011 The effects of increasing sea temperatures extend far beyond changes in species' distributions. By altering local fish abundances, temperature changes will have profound effects on the structure, functioning and services of marine ecosystems.
Harbourne, AR, Mumby, PJ, Simpson, SD
openaire +3 more sources
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
The urban ecology of Iron Age Tel Megiddo: using microvertebrate remains as ancient bio-indicators [PDF]
, 2012 Peer ...
Bar_Oz, Guy +3 more
core +1 more source