Results 91 to 100 of about 1,119,837 (309)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Spatial distribution of Oreoleuciscus potanini in evenings in the Bayan Nur lake, Мohgolia

Vìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Ekologìâ, 2009
Distribution of the altay osman in one of the lakes of Mongolia was studied in summer. Indications of the sonar GPSMAP 178 were fixed withdigital camera.
L. I. Tereshchenko, B. Mendsaihan, Y. V. Slynko, D. P. Karabanov, V. G. Tereshchenko   +4 more
doaj   +1 more source

Spatiotemporal distribution of fish schools around drifting fish aggregating devices

Fisheries Research, 2016
Omnidirectional sonar surveys were conducted in close proximity to drifting fish aggregating devices (FADs) offshore Seychelles, western Indian Ocean, to investigate the number, size, and distribution of FAD-associated fish schools. Echotrace detection techniques applied on the raw multibeam data enabled the extraction of empirical statistics regarding
Trygonis, Vasilis, Georgakarakos, Stratis, Dagorn, Laurent, Brehmer, Patrice   +3 more
openaire   +4 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Analyzing the Combined Effect of Multiple Environmental Factors on Fish Distribution, by Means of the Mixed Distribution-Decomposition Approach, as Illustrated by the East China Sea Hairtail. [PDF]

Biology (Basel), 2023
Liu Y, Cheng JH.
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Results of trawl surveys in the Bering and Okhotsk Seas in autumn 2023

Известия ТИНРО
Results of trawl surveys in the Okhotsk Sea and western Bering Sea conducted aboard RV TINRO and RV Professor Kaganovsky in the autumn of 2023 are analyzed.
A. N. Starovoitov, S. S. Ponomarev
doaj   +1 more source

Comparison of species-specific qPCR and metabarcoding methods to detect small pelagic fish distribution from open ocean environmental DNA. [PDF]

PLoS One, 2022
Yu Z, Ito SI, Wong MK, Yoshizawa S, Inoue J, Itoh S, Yukami R, Ishikawa K, Guo C, Ijichi M, Hyodo S.   +10 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Results of the trawl survey of nekton and macroplankton during preanadromous migrations of pacific salmon in the North-West Pacific in 2023

Известия ТИНРО
Results of the trawl survey in the Pacific waters at Kuril Islands within and outside EEZ of Russia conducted by RV TINRO in June-July 2023 are analyzed. Data on spatial distribution, abundance and biomass of fish, cephalopod and jellyfish species in the
A. N. Starovoytov
doaj   +1 more source