Results 71 to 80 of about 1,119,837 (309)

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

An appraisal of the efficiency of fish marketing system in Lake Chad basin [PDF]

, 2003
Fish products from the Chad Basin Lake play important role in meeting fish protein needs of Nigeria: they contribute not less than 25% of the total domestic fish supply and are significant in determining the availability of processed products and ...
Bolorunduro, P., Sule, O.D.
core  

Chromosome breakpoint distribution of damage induced in peripheral blood lymphocytes by densely ionising radiation [PDF]

, 2006
Purpose: To assess the chromosomal breakpoint distribution in human peripheral blood lymphocytes (PBL) after exposure to a low dose of high linear energy transfer (LET) α-particles using the technique of multiplex fluorescence in situ hybridisation (m ...
Anderson, RM, Goodhead, DT, Papworth, DG, Sumption, ND   +3 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Fisheries statistical bulletin, Kainji Lake, Nigeria, 1998 [PDF]

, 1999
A tabulated summary is presented of the main fisheries data collected to date (1998) by the Nigerian-German Kainji Lake Fisheries Promotion Project, together with a current overview of the fishery.

core  

Ecology of common bully (Gobiomorphus cotidianus) in the Tarawera and Rangitaiki rivers: isolation by inland distance or anthropogenic discharge? [PDF]

, 2009
Previous research has identified distinct genetic, life-history and reproductive differences between populations of common bully (Gobiomorphus cotidianus) upstream and downstream of a pulp and paper mill outfall on the Tarawera River in the Bay of Plenty,
Ahnelt H, Coombs S, Fuiman LA, Joy MK, Kelso JRM, Landman MJ, McDowall RM, Modgans J, Ovenden JR, Sprague JB, Swearer SE, Taylor JR   +11 more
core   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Temporal and Spatial Distribution Characteristics of Fish Resources in a Typical River–Lake Confluence Ecosystem During the Initial Period of Fishing Ban

Fishes
This study provides a comprehensive analysis of the spatio-temporal dynamics of fish resources in the confluence waters of Poyang Lake and the Yangtze River, focusing on the initial phase of a 10-year fishing ban implemented in January 2020.
Huifeng Li, Xujun Yu, Bingbing Wu, Lixiong Yu, Dengqiang Wang, Ke Wang, Sheng Wang, Daqing Chen, Yuefei Li, Xinbin Duan, Jie Li   +10 more
doaj   +1 more source

Ichthyoplankton seasonality in the Gulf of Salamanca, Colombian Caribbean Sea

Actualidades Biológicas, 2019
The identity, density and spatial and temporal distribution of fish larvae and eggs were investigated in the Gulf of Salamanca, Colombian Caribbean. Due to scarcity of previous studies taxonomic level was restricted to families.
Camilo Bernardo García
doaj   +1 more source

Impact of hard-bottom substrata on the small-scale distribution of fish and decapods in shallow subtidal temperate waters [PDF]

, 2012
The micro-scale spatial distribution patterns of a demersal fish and decapod crustacean assemblage were assessed in a hard-bottom kelp environment in the southern North Sea. Using quadrats along line transects, we assessed the in situ fish and crustacean
Fischer, Philipp, Wehkamp, Stephanie
core   +1 more source