Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Swimming abilities of temperate pelagic fish larvae prove that they may control their dispersion in coastal areas [PDF]
The Sense Acuity and Behavioral (SAAB) Hypothesis proposes that the swimming capabilities and sensorial acuity of temperate fish larvae allows them to find and swim towards coastal nursery areas, which are crucial for their recruitment. To gather further
Baptista, Vânia +8 more
core +2 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Fish, from both a commercial and a sporting standpoint. Based on fishes collected in Maryland only. A general treatise on fishes, setting forth the species, describing them and telling of their distribution, habits and other pertinent facts such as ...
Bean, Barton A. +2 more
core
Optimal sensing for fish school identification
Fish schooling implies an awareness of the swimmers for their companions. In flow mediated environments, in addition to visual cues, pressure and shear sensors on the fish body are critical for providing quantitative information that assists the ...
Arampatzis, Georgios +5 more
core +1 more source
Space-irrelevant scaling law for fish school sizes [PDF]
Universal scaling in the power-law size distribution of pelagic fish schools is established. The power-law exponent of size distributions is extracted through the data collapse.
Anderson +28 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Hydroacoustic method and GIS-Dashboard visualization for fish size in Banggai Sea Waters [PDF]
Estimating fish stocks, including their distribution and density, plays a vital role in the management of capture fisheries. Hydroacoustic technology is widely utilized for fish stock estimation study. In September 2022, BRIN and IPB University conducted
Windra Alivio +5 more
doaj +1 more source
Distribution of freshwater fish in the south-western corner of Australia [PDF]
This study investigates the distribution of freshwater fishes in the Busselton to Walpole Region. A total of 311 sites in 19 major catchments along the south-west coast from Capel to Walpole, were sampled using a variety of methods.
Gill, H.S., Morgan, D.L., Potter, I.C.
core +1 more source

