Results 241 to 250 of about 1,437,720 (348)

Stabilized Ion Selectivity Corrects Activation Drift in Kalium Channelrhodopsins

Advanced Science, EarlyView.
As newly emerged optogenetic tools, potassium channelrhodopsins (KCRs) can drift from inhibition to activation during illumination as K⁺ selectivity declines. It is shown that both the absolute K⁺/Na⁺ permeability ratio and its stability over time govern this drift, identify KCR1‐C29D as a reliably inhibitory variant, and outline design principles for ...
Xiao Duan, Chong Zhang, Stanislav Ott, Zhiyi Zhang, Christiane Ruse, Sven Dannhäuser, Robert Jacobi, Nadine Ehmann, Divya Sachidanandan, Georg Nagel, Manfred Heckmann, Robert J. Kittel, Alexander Gottschalk, Adam Claridge‐Chang, Shiqiang Gao   +14 more
wiley   +1 more source

A Coding SNP in GmPM30 Enhances Soybean Salinity Tolerance and Yield through the GmLEA1‐GmPM30‐GmLEC1 Module

Advanced Science, EarlyView.
A natural variation in soybean PM30, GmPM30‐HapT, confers greater salt tolerance than GmPM30‐HapC via stronger GmLEA1‐GmPM30‐GmLEC1 interactions. Pyramiding their elite haplotypes yields additive gains in salt tolerance and yield, establishing a novel workflow linking evolutionary genomics, molecular mechanisms, and breeding applications via the module
Shiyu Huang, Yuhan Xia, Jingting Yang, Yujun Si, Xue Chen, Hao Zhang, Tianshi Liu, Wenyu Zheng, Xin Chen, Zhongjuan Zhao, Xiaojian Zheng, Qing Lu, Shuo Li, Fengning Xiang   +13 more
wiley   +1 more source

Applying the FAO surveillance evaluation tool (SET) to assess the fish farming disease surveillance system in Spain. [PDF]

Front Vet Sci
Muniesa A, Ruiz-Zarzuela I, Lamielle G, Von Dobschuetz S, Furones D, Rodgers C, Basurco B.   +6 more
europepmc   +1 more source

Therapeutic Reprogramming of Glioblastoma Phenotypic States Using Multifunctional Heparin Nanoparticles

Advanced Science, EarlyView.
This study presents heparin‐derived nanoparticles (HP‐NPs) as a novel precision medicine platform that combines therapeutic and delivery functions. HP‐NPs target drug‐resistant glioblastoma stem cells, reprogramming them into a drug‐sensitive phenotype and significantly reducing tumor progression.
Vadim Le Joncour, Austin D. Evans, Camilla Karoliina Bergström, Vignesh Kumar Rangasami, Sumanta Samanta, Nithiyanandan Krishnan, Yuji Teramura, Bo Nilsson, Patricia Hedenqvist, Elin Manell, Jons Hilborn, Marianne‐Jensen Waern, Oommen P. Varghese, Pirjo Laakkonen, Oommen P. Oommen   +14 more
wiley   +1 more source

Economic feasibility study of organic and conventional fish farming systems of Indian major carps. [PDF]

Sci Rep
Beg MM, Roy SM, Moulick S, Mandal B, Kim T, Mal BC.   +5 more
europepmc   +1 more source

The aggregation effect of offshore mussel farming on pelagic fishes [PDF]

Danielle Bridger, Martin J. Attrill, Siân E. Rees, Emma V. Sheehan   +3 more
openalex   +1 more source

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

Advanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang, Shuang Li, Man Li, Wenke Zhou, Jianqing Zhang, Zhenfu Wu, Zhaoqi Mao, Juan Wan, Xinhao Tang, Baoping Zheng, Qiang Liu, Zhendong Li, Xiaobing Jiang, Qingping Wu, Youfan Ye, Haijun Wang   +15 more
wiley   +1 more source

Distribution of extended-spectrum β-lactamase producing Escherichia coli genes in an integrated poultry-fish farming system in Bogor, Indonesia. [PDF]

Vet World
Handayani KS, Setiyono A, Lukman DW, Pisestyani H, Rahayu P.   +4 more
europepmc   +1 more source

Ecology and larval population dynamics of the primary malaria vector Nyssorhynchus darlingi in a high transmission setting dominated by fish farming in western Amazonian Brazil. [PDF]

PLoS One, 2021
Rufalco-Moutinho P, Moura Kadri S, Peres Alonso D, Moreno M, Carrasco-Escobar G, Prussing C, Gamboa D, Vinetz JM, Mureb Sallum MA, Conn JE, Martins Ribolla PE.   +10 more
europepmc   +1 more source

The Effects of Marketing Mix on Small Fish Farming Business Performance

, 2019
A.W. Nurul Fitriah, Siti Nabila Rosdi, M. Mohd Rosli, Nora’Aini Mustapha, Zuraimi Abdul Aziz, Wan Mohd Yusof Wan Ibrahim, Mohd Shahril Nizam Md Radzi, N.Z. Aniesha, Abdul Aziz Yaacob   +8 more
openalex   +1 more source