Results 291 to 300 of about 1,437,720 (348)

Insect I‐Type Lysozymes Function as Antiviral Proteases by Forming Biomolecular Condensates

Advanced Science, EarlyView.
Upon rice viral infection, the insect vector activates the Toll–MyD88–Dorsal signaling cascade, inducing i‐type lysozyme (Lyz‐I1) expression. Lyz‐I1 functions as an antiviral protease through its conserved catalytic dyad Glu/Asp (E/D), mediating cleavage of viral proteins at specific Lys (K) residues.
Yu Du, Yuqing Xiao, Manman Hu, Jinhua Yang, You Li, Taiyun Wei   +5 more
wiley   +1 more source

Genome‐Wide Protein Interaction Analysis in Parasitic Gyrodactylus Flatworms–Fish Hosts System and Drug Target Identification

Advanced Science, EarlyView.
Genomic data offer a powerful tool for studying the molecular interactions between parasites and their hosts, but they remain scarce for parasitic monogenean flatworms. This study presents the first high‐quality phased genome assembly for monogeneans (Gyrodactylus kobayashii), and uses it to predict key interacting proteins between monogenean parasite ‐
Dong Zhang, Jie‐Mei Zhao, Chuan‐Yu Xiang, Yi‐Wen Ma, Hong‐Peng Lei, Yu‐Ying Shi, Shun Zhou, Xiaofei Zeng, Jinsong Chen, Fei Liu, Benhe Zeng, Rui Song, Ye Hu, Feng Zhang, Xiang Liu, Wen‐Xiang Li, Gui‐Tang Wang, Ivan Jakovlić   +17 more
wiley   +1 more source

The High‐Altitude Adaptation Characteristics of Microbiota‐Host Cross‐Talk in Yak Gastrointestinal Track

Advanced Science, EarlyView.
In this study, a single‐cell atlas of 117,019 yak gastrointestinal cells across 54 subtypes identified HNF4A and SREBF2 as key transcription factors targeting MYO6 gene. Cross‐species and multi‐omics analyses reveals epithelial cells as key regulators that, through interactions with microbes, particularly Bacillus, facilitate flexible energy supply and
Chun Huang, Minghao Zhang, Qingbo Zheng, Qinran Yu, Guowu Yang, Wenwen Ren, Xiaoming Ma, Yongfu La, Pengjia Bao, Min Chu, Xian Guo, Chunnian Liang, Ping Yan   +12 more
wiley   +1 more source

Bio‐Based Wax Interfaces for Droplet Energy Harvesting at Fluoropolymer‐Like Output Levels

Advanced Science, EarlyView.
Replacing unsustainable fluorinated polymers in droplet‐based energy harvesters is usually limited by low power outputs, but carefully selected bio‐based polymers are capable of creating fluoropolymer‐like voltage outputs. Abstract Droplet impact and rebound on solid surfaces has emerged as a promising method for energy harvesting, typically ...
Behnam Kamare, Mahla Shahabi, Matteo Carpi de Resmini, Tiago Fernandes, Fabian Meder   +4 more
wiley   +1 more source

Medicago Sativa L. Saponin‐Driven Lactobacillus Intestinalis Restores Intestinal Stemness in Naturally Aged Mice via the Bile Acid‐FXR‐Wnt Signaling Axis

Advanced Science, EarlyView.
This study examines the mechanism by which alfalfa saponin (AS) regulates intestinal stemness via modulation of the gut microbiota. The results indicate that AS significantly increases the abundance of Lactobacillus intestinalis, which subsequently activates Wnt signaling via bile acid metabolism and enhances intestinal stemness. These findings provide
Mengqi Liu, Jiamin Sun, Zuyang Jia, Yalei Cui, Xiaoyan Zhu, Zhichang Wang, Hao Sun, Boshuai Liu, Yinghua Shi   +8 more
wiley   +1 more source

Superwettable‐Membrane‐Assisted Extraction and Separation as a General Method for Removal of Organic Pollutants From Water

Advanced Science, EarlyView.
An integrated liquid‐liquid extraction and in situ superwettable membrane separation system is developed for efficient removal of organic pollutants from wastewater. After being treated with this novel technology, the residual organic pollutants are < 1.5 ppm with a removal efficiency > 95.5% and a TOC < 40 ppm, demonstrating a scalable and sustainable
Deqi Wang, Ting Zhang, Fan Min, Yifeng Gao, Jiaming Zhu, Ganhua Xie, Zonglin Chu   +6 more
wiley   +1 more source

RNAi Regulator C3PO Promotes Arbovirus Infection in Insect Vectors

Advanced Science, EarlyView.
RNA interference (RNAi) is vital for eukaryotes to defend against virus infection. The C3PO complex takes part in RNAi but its role in regulating viral infection remains unclear. This work finds that insect C3PO facilitates arbovirus replication by degrading precursors of miRNAs, especially miR‐971‐3p.
Yan Xiao, Tianyu Guan, Qianfeng Xia, Chen Chen, Qian Wang, Lan Luo, Hong Lu, Feng Cui   +7 more
wiley   +1 more source

Toward Sustainable Pesticide Application: Bridging Efficacy and Food Safety

Advanced Science, EarlyView.
A fully bio‐based lignin coacervate system is developed for pesticide delivery, enhancing leaf retention, UV resistance, adhesion, and wetting. The formulation enables pH/laccase‐triggered release for prolonged action, reduces ecological toxicity, and is fully washable, reconciling agricultural efficacy with food and environmental safety.
Xuan Li, Janar Tursen, Wanbin Zhu, Xufeng Yuan, Hongliang Wang   +4 more
wiley   +1 more source

A Robust Solar Evaporator with Hierarchical Architecture for Ultrahigh Efficiency and Large‐Scale Zero‐Liquid‐Discharge Desalination

Advanced Science, EarlyView.
This study presents a low‐carbon footprint, robust 3D (three‐dimensional) evaporator featuring multi‐level low‐tortuosity channels for highly efficient desalination. It achieves an outstanding average evaporation rate of 8.1 kg m−2 h−1, salt collection rate of 1.95 kg m−2 h−1, and durability in high‐salinity brine.
Lili Sun, Ning Wang, Ning Hu, Yongyun Zhao, Libin Zhao, Wenbo Chen   +5 more
wiley   +1 more source

Charge Injection and Transport in an Isoindigo‐Based Polymer Transistor

Advanced Electronic Materials, EarlyView.
This study presents the charge injection and transport properties of field‐effect transistors based on an isoindigo‐bithiophene donor‐acceptor polymer semiconductor contacted with thiolated self‐assembled monolayer (SAM)‐functionalized electrodes. Temperature‐dependent contact characteristics are measured and simulated.
Zuchong Yang, Daniele Zucchelli, Melissa Berteau‐Rainville, Qi Wang, Sydney Mikulin, Ingo Salzmann, Steffen Duhm, Fabrizio Torricelli, Emanuele Orgiu   +8 more
wiley   +1 more source