Results 31 to 40 of about 79,500 (263)
What Happens in an Estuary Doesn't Stay There: Patterns of Biotic Connectivity Resulting from Long Term Ecological Research [PDF]
Oceanography, 2013 The paucity of data on migratory connections and an incomplete understanding of how mobile organisms use geographically separate areas have been obstacles to understanding coastal dynamics.
Martha E. Mather +4 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Principle and design of hatch operation system for fish migrating upstream-downstream of the discharge sill [PDF]
Acta Scientiarum Polonorum. Formatio Circumiectus, 2016 To improve fish migration and restore local lotic ecosystems, it is necessary to consider the various current hydro-construction methods. There have been partial successes in systems that improve fish passage over various obstacles but new approaches ...
Răzvan G.Voicu, Kelly N. Miles
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Frontiers in Freshwater ScienceIntroductionThis study examines the dynamics and characteristics of seasonal fish migration into the floodplain of a large lowland river.MethodsFor continuous recording of the number of fish migrating upstream and downstream, and their size composition ...
Andrey A. Chemagin +3 more
doaj +1 more source
PLoS ONE, 2018 Otolith strontium and multi-year mark-recapture information were used to characterize associations between migration patterns and spawning frequencies in an anadromous Dolly Varden (Salvelinus malma) population (Rat River, Northwest Territories, Canada ...
Colin P Gallagher +3 more
doaj +1 more source
Fisheries & Aquatic Life, 2022 The poor results of lake-migratory brown trout, Salmo trutta lacustris L., restoration in Lake Hańcza Nature Reserve prompted undertaking the current study that sought to verify if hatchery-reared fish age 2+ can survive the critical period of ...
Mierzejewska Katarzyna +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Towards understanding the presence of abundant fish in running iishana
Namibian Journal of Environment, 2021 Although the iishana (seasonal watercourses) deltaic system in northern Namibia and southern Angola is usually dry, millions of fish populate the more than 100 000 km2 area during high floods that occur irregularly about once in three years.
BCW van der Waal +2 more
doaj +1 more source