Results 91 to 100 of about 235,085 (295)

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Information Submanifold Based on SPD Matrices and Its Applications to Sensor Networks

Entropy, 2017
In this paper, firstly, manifoldPD(n)consisting of alln×nsymmetric positive-definite matrices is introduced based on matrix information geometry; Secondly, the geometrical structures of information submanifold ofPD(n)are presented including metric ...
Hao Xu, Huafei Sun, Aung Naing Win
doaj   +1 more source

Inadequacies of the Fisher information matrix in gravitational-wave parameter estimation [PDF]

, 2013
Carl L. Rodriguez, B. Farr, Will M. Farr, Ilya Mandel   +3 more
openalex   +1 more source

Entropies and Fisher information matrix for extended beta distribution

Applied Mathematical Sciences, 2015
The extended beta type 1 distribution has the probability density function proportional to x 1 (1 x) 1 exp[ =x (1 x)], 0 < x < 1. In this article, we derive the Fisher information matrix and entropies such as R enyi and Shannon for the extended beta type 1 distribution.
Nagar, Daya Krishna, Zarrazola Rivera, Edwin de Jesús, Sánchez Herrera, Luz Estela   +2 more
openaire   +3 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

A Sandwich with Water: Bayesian & Frequentist Inference Under Model Misspecification

ARC Geophysical Research
In this paper we review basic elements of Frequentist inference, specifically maximum likelihood (ML) and M-estimation, to point out a critical flaw of Bayesian methods for hydrologic model training and uncertainty quantification.
Jasper A. Vrugt, Cees G.H. Diks, Ramon de Punder, Peter Grünwald   +3 more
doaj   +2 more sources

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle, Silvana Sarria‐Estrada, Thomas Bonduelle, Bertram Daniel Dynesen, Manuel Toledo, Zhu Chung Che, Kjell Heuser, Anastasios Chatzikonstantinou, Jérôme Aupy, Udaya Seneviratne, Estevo Santamarina Perez, Christoph Patrick Beier   +11 more
wiley   +1 more source

Visual Active SLAM Method Considering Measurement and State Uncertainty for Space Exploration

Aerospace
This paper presents a visual active SLAM method considering measurement and state uncertainty for space exploration in urban search and rescue environments. An uncertainty evaluation method based on the Fisher Information Matrix (FIM) is studied from the
Yao Zhao, Zhi Xiong, Jingqi Wang, Lin Zhang, Pascual Campoy   +4 more
doaj   +1 more source