Single-nucleus and machine-learning integration identifies HLA-DRA and FTL as immune-metabolic axes and traditional Chinese medicine-targetable hubs in calcific aortic valve disease. [PDF]
Zhao Q +6 more
europepmc +1 more source
Mechanoregulatory Effects of Cell‐Scale Microwells on Epithelial Cell Phenotype
In small polycaprolactone microwells, A549 epithelial cells span well edges, in contrast to cells growing on flat substrates. Focal adhesion sites (yellow) concentrate at topographic boundaries, while cytoskeletal tension (magenta stress fibers) is transmitted to the nucleus (blue), reducing nuclear sphericity.
Ruiwen He +10 more
wiley +1 more source
Protocol for simultaneous profiling of N- and O-glycans on glycoproteins using a one-pot format. [PDF]
Knizner KT +5 more
europepmc +1 more source
ABSTRACT Engineering living matter has great clinical potential to deliver functional replacement organs. However, clinical translation remains hampered by the current inability to maintain viability of clinically relevant‐sized constructs. During the pre‐vascular phase, implants rely on nutrient diffusion for survival, which is insufficient at ...
Melvin Gurian +5 more
wiley +1 more source
Protocol for combining BMP, MEK, WNT inhibition and iNGN2 to enable rapid neuronal differentiation and regional patterning from hiPSCs. [PDF]
Habich C +4 more
europepmc +1 more source
Cephalopod‐inspired photonic microparticles with dynamic structural coloration are fabricated via confined self‐assembly of linear block copolymers into ellipsoids containing stacked lamellae. Embedded superparamagnetic nanoparticles enable rapid magnetic alignment, restoring vivid, angle‐dependent color.
Gianluca Mazzotta +8 more
wiley +1 more source
Density Functional Theory and Information-Theoretic Diagnostics of Quantum Phase Transitions. [PDF]
Romera E, Nagy Á.
europepmc +1 more source
An algorithm for computing the asymptotic Fisher information matrix for seasonal SISO models
André Klein, Guy Mélard
openalex +1 more source
Multi-Objective Optimization of Experiments Using Curvature and Fisher Information Matrix
Erica Manesso +2 more
openalex +2 more sources

