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Fisher Information in Helmholtz–Boltzmann Thermodynamics of Mechanical Systems

Foundations
In this paper, we review Helmholtz–Boltzmann thermodynamics for mechanical systems depending on parameters, and we compute the Fisher information matrix for the associated probability density.
Marco Favretti
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Comparing the Fisher information matrix in record values and random observations for the general class of exponentiated distributions [PDF]

Journal of Statistical Theory and Applications (JSTA), 2017
In this paper, the Fisher information matrix (FIM) contained in n record values is considered for the two parameter distributions belong to the exponentiated and inverse exponentiated class of distributions. The problem of existence and uniqueness of the
Fatih Kızılaslan
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MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Weak convexity of Fisher information matrix and superresolved localization of blinking sources of light

Physical Review Research
A group of techniques known by the general name of single-molecule localization microscopy reaches a nanometer-scale spatial resolution of point light emitters, well below the diffraction limit of traditional microscopy.
Dmitri B. Horoshko, Alexander B. Mikhalychev, Fedor Jelezko, Polina P. Kuzhir   +3 more
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Trade-Offs of Diagonal Fisher Information Matrix Estimators

Advances in Neural Information Processing Systems 37
The Fisher information matrix can be used to characterize the local geometry of the parameter space of neural networks. It elucidates insightful theories and useful tools to understand and optimize neural networks. Given its high computational cost, practitioners often use random estimators and evaluate only the diagonal entries. We examine two popular
Alexander Soen, Ke Sun 0001
openaire   +3 more sources

Transformed statistical distance measures and the fisher information matrix

Linear Algebra and its Applications, 2012
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Klein, A., Spreij, P.J.C.
openaire   +4 more sources

Asymptotically Constant-Risk Predictive Densities When the Distributions of Data and Target Variables Are Different

Entropy, 2014
We investigate the asymptotic construction of constant-risk Bayesian predictive densities under the Kullback–Leibler risk when the distributions of data and target variables are different and have a common unknown parameter. It is known that the Kullback–
Keisuke Yano, Fumiyasu Komaki
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

A stronger version of matrix convexity as applied to functions of Hermitian matrices

Journal of Inequalities and Applications, 1999
A stronger version of matrix convexity, called hyperconvexity is introduced. It is shown that the function is hyperconvex on the set of Hermitian matrices and is hyperconvex on the set of positive definite Hermitian matrices. The new concept makes it
Kagan Abram, Smith Paul J
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