Results 181 to 190 of about 1,060,583 (384)
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Notes on Oneida Lake Fish and Fisheries [PDF]
, 1916 Chas. C. Adams, T. L. Hankinson
openalex +1 more source
Small-scale fisheries development in Nigeria: Status, prospects, constraints/recommended solutions [PDF]
, 1986 The small-scale fisheries sector has been contributing immensely towards domestic fish production in Nigeria. Despite considerable contributions by the small-scale fisherman of Nigeria, with few exceptions, they continue to live at the margin of ...
Aderounmu, A.A.
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Molecular Oncology, EarlyView.Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li +12 more
wiley +1 more source
Approaches to Improving CPR Management Performance in Developing Countries: Best Practice [PDF]
, 2005 The apparent and widespread lack of success over the past 50 years in attempting to manage the exploitation of Common Pool Resources in a sustainable manner is a serious concern for society.
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Molecular Oncology, EarlyView.Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi +12 more
wiley +1 more source
APFIC Regional Workshop on "Mainstreaming Fisheries Co-management" [PDF]
, 2005 This is the report of the APFIC regional workshop on "Mainstreaming fisheries co-management" held in Siem Reap, Cambodia from August 9-12, 2005 . The goal of the workshop was to provide a forum to learn from past experience and to promote devolved ...
David Brown +2 more
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Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs
Molecular Oncology, EarlyView.In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza +3 more
wiley +1 more source