Results 281 to 290 of about 835,199 (355)
In Vitro Modeling of Natural Killer Cell Cytotoxicity to Inform Personalized ALS Therapeutics
ABSTRACT Objective Natural killer (NK) cells might contribute to motor neuron death in amyotrophic lateral sclerosis (ALS) through direct cytotoxicity, a process that could be inhibited with the FDA‐approved JAK/STAT pathway inhibitor, tofacitinib. This study aimed to verify that tofacitinib can suppress NK cell cytotoxicity, investigate if immune cell
Benjamin J. Murdock+8 more
wiley +1 more source
Genetic Diversity and Structure of Korean Pacific Oyster (<i>Crassostrea gigas</i>) for Determining Selective Breeding Groups. [PDF]
Kim KR+6 more
europepmc +1 more source
ABSTRACT Objective To compare the effectiveness of high‐efficacy treatments (HET) and low‐efficacy treatments (LET) in NMOSD patients with anti‐aquaporin‐4 antibodies (AQP4‐ab). Methods In this multi‐center study, we analyzed 183 AQP4‐ab seropositive NMOSD patients who received immunosuppressive treatments (IST).
Xiang Li+10 more
wiley +1 more source
Drivers and effects of fish-for-sex related single parenthood in a fishing coastal community in Ghana. [PDF]
Kyei-Gyamfi S, Kyei-Arthur F.
europepmc +1 more source
ABSTRACT Purpose This study aimed to explore the association between quantitative shape irregularity and density heterogeneity of hematomas and hematoma expansion (HE) for intracerebral hemorrhage (ICH) patients. Methods This cohort study included patients arriving within 24 h of symptom onset between August 2021 and July 2022 as the derivation cohort ...
Zeqiang Ji+11 more
wiley +1 more source
Antibiotics governance in aquaculture: knowledge, practices, and challenges among stakeholders on the Volta Lake in Ghana. [PDF]
Dandi SO+10 more
europepmc +1 more source
ABSTRACT Objective The Apolipoprotein (APOE) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular vesicles (NDEVs), we sought to identify biomarkers of cognitive resilience and their interplay with APOE ...
Apostolos Manolopoulos+17 more
wiley +1 more source
A novel approach combining YOLO and DeepSORT for detecting and counting live fish in natural environments through video. [PDF]
Khiem NM+3 more
europepmc +1 more source