Results 71 to 80 of about 224,163 (286)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Studying Kenai River Fisheries’ Social-Ecological Drivers Using a Holistic Fisheries Agent-Based Model: Implications for Policy and Adaptive Capacity

Fishes, 2019
Alaska’s salmon fisheries are one of the more intensely managed natural resources in the world. The state’s salmon fisheries support recreational, subsistence, and commercial harvest with multiple billions of dollars flowing into the economy,
Maxwell Franklin, Martin Cenek, E. Jamie Trammell   +2 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Demographic response of osprey within the lower Chesapeake Bay to fluctuations in menhaden stock

Frontiers in Marine Science
Forage fish support the largest fisheries in the world and play a vital role in marine food webs by transferring energy from plankton to consumers within higher trophic levels.
Bryan D. Watts, Bryan D. Watts, Christine H. Stinson, Peter K. McLean, K. Andrew Glass, K. Andrew Glass, Michael H. Academia, Michael H. Academia, Mitchell A. Byrd, Mitchell A. Byrd   +9 more
doaj   +1 more source

‘Reported’ versus ‘likely’ fisheries catches of four Mediterranean countries

Scientia Marina, 2014
The fisheries catch statistics that member countries report annually to the Food and Agriculture Organization of the United Nations were compared, for the years 1950 to 2010, with ‘reconstructed’, and more likely catch data from the Mediterranean coasts ...
Daniel Pauly, Aylin Ulman, Chiara Piroddi, Elise Bultel, Marta Coll   +4 more
doaj   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Application of the food-energy-water nexus to six seafood supply chains: hearing from wild and farmed seafood supply chain actors in the United States, Norway, and Vietnam

Frontiers in Sustainable Food Systems
IntroductionThe food-energy-water (FEW) nexus highlights the interdependencies between the systems that people rely on for these essential resources. For example, globally, over two thirds of freshwater withdrawals are used to produce food, and another ...
Jillian P. Fry, Rachel E. Scroggins, Taryn M. Garlock, David C. Love, David C. Love, Frank Asche, Frank Asche, Mark T. Brown, Elizabeth M. Nussbaumer, Elizabeth M. Nussbaumer, Ly Nguyen, Lekelia D. Jenkins, James Anderson, James Anderson, Roni A. Neff, Roni A. Neff   +15 more
doaj   +1 more source

Reconciling fisheries catch and ocean productivity [PDF]

, 2017
Charles A. Stock, Jasmin G. John, Ryan R. Rykaczewski, Rebecca G. Asch, William W. L. Cheung, John P. Dunne, Kevin D. Friedland, Vicky W. Y. Lam, Jorge L. Sarmiento, Reg Watson   +9 more
openalex   +1 more source

A Bioeconomic Analysis of the Sandfish (Arctoscopus japonicus) Management Policies of the Eastern Sea Danish Fishery in Korea [PDF]

, 2021
Ji-Hoon Choi, Jae-Bong Lee, Sangchul Yoon, Do-Hoon Kim   +3 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source