Results 121 to 130 of about 440,418 (379)

Expression and purification of E140 protein antigen fragments of Plasmodium vivax and Plasmodium berghei for serological assays

open access: yesFEBS Open Bio, EarlyView.
We provide a step‐by‐step guide for producing E140 antigen fragments from Plasmodium berghei (Pb1) and Plasmodium vivax (Pv1). Pb1/Pv1 are expressed in E. coli, solubilized by freeze–thawing, refolded by slow dilution, purified by affinity chromatography (IMAC), then concentrated and subjected to quality control.
Rodolfo Ferreira Marques   +5 more
wiley   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

open access: yesFEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy   +14 more
wiley   +1 more source

A potential tumor suppressor role of PLK2 in glioblastoma

open access: yesFEBS Open Bio, EarlyView.
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia   +5 more
wiley   +1 more source

Ecolabelling and Fisheries Management [PDF]

open access: yes, 2004
RAFMS (Rapid Appraisal of Fisheries Managment Systems) designed by ICLARM is a semistructural research tool designed to quickly document and evaluate exisiting local-level fisheries management systems in a given coastal community.
Len Garces   +3 more
core  

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

open access: yesFEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel   +13 more
wiley   +1 more source

Ecosystem-Based Fisheries Management [PDF]

open access: yes, 2014
The fish on the end of your line, the little forage fish that feed the big fish, the corals that build reef habitats, and the catch of the day in your favorite restaurant are interconnected parts of a vibrant ocean ecosystem.Ensuring the long-term health

core  

TRANSACTION COSTS AND FISHERIES CO-MANAGEMENT [PDF]

open access: yes
Fisheries co-management as an alternative to centralized command and control fisheries management is often suggested as a solution to the problems of fisheries resource use conflicts and overexploitation.
Abdullah, Nik Mustapha Raja   +2 more
core   +1 more source

Feasibility of fisheries co-management in Africa [PDF]

open access: yes, 2004
The current, highly centralized approach to fisheries management seems to be incapable of coping with escalating resource depletion and environmental degradation. Co-management has been identified as an alternative. This paper compares various approaches
Brummett, R., Khan, A.S., Mikkola, H.
core  

Novel CT radiomics models for the postoperative prediction of early recurrence of resectable pancreatic adenocarcinoma: A single‐center retrospective study in China

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To assess the predictive capability of CT radiomics features for early recurrence (ER) of pancreatic ductal adenocarcinoma (PDAC). Methods Postoperative PDAC patients were retrospectively selected, all of whom had undergone preoperative CT imaging and surgery. Both patients with resectable or borderline‐resectable pancreatic cancer met
Xinze Du   +7 more
wiley   +1 more source

Approaches to Improving CPR Management Performance in Developing Countries: Best Practice [PDF]

open access: yes, 2005
The apparent and widespread lack of success over the past 50 years in attempting to manage the exploitation of Common Pool Resources in a sustainable manner is a serious concern for society.

core  

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