Objective JAK inhibitors (JAKi) have shown promising effects in early‐phase studies of systemic sclerosis (SSc). We aimed to assess the safety and explore the effectiveness of JAKi compared to conventional immunosuppressants in SSc. Methods A longitudinal retrospective study of the European Scleroderma Trials and Research Group (EUSTAR) cohort was ...
Stefano Di Donato +27 more
wiley +1 more source
Responses of Fish Zeta Diversity (ζ) to Human Pressure and Cumulative Effects: A Feasibility Study of Fishing Ban Measures in the Pearl River Basin, China. [PDF]
He J, Liu H, Bi X, Wu Z.
europepmc +1 more source
Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki +6 more
wiley +1 more source
Seasonal Spatial Distribution Patterns of <i>Abralia multihamata</i> in the East China Sea Region: Predictions Under Various Climate Scenarios. [PDF]
Xu M, Liu S, Yang C, Yang L.
europepmc +1 more source
Biomedical research involving US veterans continues to advance health care beyond the Veterans Health Administration. This is particularly true in rheumatoid arthritis (RA), where veteran‐centric research has uncovered novel insights into pathogenesis, risk factors, and disease manifestations, informing clinical care and research across both veteran ...
Austin M. Wheeler +20 more
wiley +1 more source
Prediction greenhouse gas emissions from road freight flow in South Korea for sustainable transportation planning. [PDF]
Nam H, Byun J, Nam H.
europepmc +1 more source
Objective Systemic sclerosis (SSc) is characterized by cardiovascular risk excess not fully explained by traditional factors. Whether the severity of microvascular damage correlates with structural subclinical atherosclerosis remains unclear. We investigated the relationship between nailfold videocapillaroscopy (NVC) abnormalities and carotid ...
Eugenio Capparelli +13 more
wiley +1 more source
Heat Stress and Anthropogenic Substrates: Molecular and Behavioral Adaptation of <i>Metridium senile</i> in Human-Modified Marine Environments. [PDF]
Teng G, Chen W, Shan X, Zhu Q, Jin X.
europepmc +1 more source
Predicting upwelling dynamics in the South Sea of Java, Indonesia: A deep learning approach with ConvLSTM and 3D-CNN. [PDF]
Rantini D +9 more
europepmc +1 more source

