Results 41 to 50 of about 10,722 (263)
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
The Canadian Fisheries Industry: Retrospect and Prospect
Without question, Canadian domestic policy has had an influence on the development of the fisheries staple industry – from its National Policy to its subsidization of both fishers and, more recently its effort to conserve of fish stocks. In this respect Laxer is correct in allocating “blame” for the current dire status of the fisheries industry where ...
openaire +2 more sources
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
KEBIJAKAN KERAJAAN DAN PERTUMBUHAN INDUSTRI PERIKANAN DI SELAT MALAKA SEBELUM PENJAJAHAN
This paper aims to prove the relation of Siak Kingdom policy to fishery industry in Malacca Strait. Because the Strait Malacca have rich by fishes. The archeologis fact eksplans many of clem shell of wasting of the coastal communities wastes.
Azmi Fitrisia
doaj +1 more source
We aimed to investigate the effects of dietary alpha-lipoic acid (α-LA) on the growth performance, serum biochemical indexes, liver morphology, antioxidant capacity, and transcriptome of juvenile hybrid groupers (Epinephelus fuscoguttatus♀ × Epinephelus ...
Guanghai Ou +8 more
doaj +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Disintegration of Oki Fishery Industry
The Oki Islands, or the Province of Oki, as described in “Engishiki” a court document of the 11th century, was noted forr her fishery products. In the amount of the products, according to the above document, Oki ranked third, the other two being Wakasa and Shima. Dried sea-ears, boiled sea-cucumber and dried cattle-fish were the principal products.
openaire +3 more sources
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Fisheries industry strategy in Indonesia
Abstract Over the past few years, fishery growth has always exceeded economic growth in Indonesia. Based on this performance, more focused policies are needed to manage it. This study aims to develop a strategy for the fishing industry, specifically related to the center of the fisheries processing industry in Indonesia, with a ...
null Miar +4 more
openaire +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source

