Results 41 to 50 of about 11,090 (264)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

R-SWARA and COPRAS Integration for Evaluating Third-Party Logistics Providers

Ingeniería
Context: Evaluating third-party logistics (3PL) providers is a complex task since multiple criteria assessed by experts with potentially diverse perspectives are involved, leading to varying scores based on individual prioritizations. This study attempts
Adhie Prayogo, Muhammad Mujiya Ulkhaq
doaj   +1 more source

The Canadian Fisheries Industry: Retrospect and Prospect

Canadian Political Science Review, 2007
Without question, Canadian domestic policy has had an influence on the development of the fisheries staple industry – from its National Policy to its subsidization of both fishers and, more recently its effort to conserve of fish stocks. In this respect Laxer is correct in allocating “blame” for the current dire status of the fisheries industry where ...
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Economic Study Of Tuna Loin Industry Development In Kaur Regency, Bengkulu Province

Journal of Aquaculture Science, 2021
Tuna fishery production in Bengkulu Province is mainly produced by fishermen in Kaur Regency. The tuna fishery business in Kaur Regency is still small scale and traditional. The potential of tuna fish resources that quite large in the Kaur Regency waters,
Zamdial Zamdial, Dede Hartono, Dede Hartono, Tri Anugrah Yudesta, Tri Anugrah Yudesta   +4 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Disintegration of Oki Fishery Industry

Geographical Review of Japan, 1951
The Oki Islands, or the Province of Oki, as described in “Engishiki” a court document of the 11th century, was noted forr her fishery products. In the amount of the products, according to the above document, Oki ranked third, the other two being Wakasa and Shima. Dried sea-ears, boiled sea-cucumber and dried cattle-fish were the principal products.
openaire   +3 more sources

KEBIJAKAN KERAJAAN DAN PERTUMBUHAN INDUSTRI PERIKANAN DI SELAT MALAKA SEBELUM PENJAJAHAN

Humanus: Jurnal Ilmiah Ilmu-ilmu Humaniora, 2019
This paper aims to prove the relation of Siak Kingdom policy to fishery industry in Malacca Strait. Because the Strait Malacca have rich by fishes. The archeologis fact eksplans many of clem shell of wasting of the coastal communities wastes.
Azmi Fitrisia
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Fisheries industry strategy in Indonesia

IOP Conference Series: Earth and Environmental Science, 2020
Abstract Over the past few years, fishery growth has always exceeded economic growth in Indonesia. Based on this performance, more focused policies are needed to manage it. This study aims to develop a strategy for the fishing industry, specifically related to the center of the fisheries processing industry in Indonesia, with a ...
null Miar, null Firmansyah, Shanty Oktavilia, Dita W Puspita, Ryan Prayogi   +4 more
openaire   +1 more source