Results 41 to 50 of about 48,071 (305)
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
White tail disease (WTD) is caused by the Macrobrachium rosenbergii nodavirus (MrNV) and an extra-small virus (XSV). MrNV belongs to the Nodaviridae family.
Gwang Il Jang +8 more
doaj +1 more source
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
A theoretical analysis of season length restrictions in fisheries management
This paper studies season length restrictions in fisheries management from an ecological-economic perspective. We first construct a model of a stylized fishery in which season length restrictions are used to manage the fishery.
Qing Xu, Amitrajeet A. Batabyal
doaj +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Coastal Rural Development Planning: Fishery Food Management
The planning of coastal villages based on fishery food management is intended as an approach to strengthen coastal communities to alleviate rural poverty.
Rudianto Rudianto, Uun Yanuhar
doaj
PERAN KELEMBAGAAN LOKAL DALAM PENGELOLAAN PERIKANAN DI ERA DESENTRALISASI
. The purpose of this research is to analyze the role of Panglima Laot in the management of fishery resources in Sabang Island. To be able to understand the fisheries management that involves the role of the community in the form of local institutions, a
Mustaqim - Mustaqim
doaj +1 more source
The consumption of cultured crustaceans has been steadily increasing, and Pacific whiteleg shrimp (Litopenaeus vannamei) are major cultivated invertebrates worldwide. However, shrimp productivity faces a variety of challenges, mainly related to outbreaks
Bo-Seong Kim +7 more
doaj +1 more source

