Results 131 to 140 of about 1,556,109 (399)

Southern California partyboat sampling study Quarterly Report no. 3 [PDF]

open access: yes, 1976
During the period January 1 to March 31, 1976, Department personnel made 139 sampling trips aboard southern California partyboats. A total of 22,122 fishes from 73 species was identified and measured. Otoliths were removed from 1,536 rockfish carcasses
Maxwell, William D., Schultze, Donald L.
core   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

Effects of Astragalus membranaceus by-product on pellet quality, mold growth and resistance of Crucian carp (Carassius auratus) against Aeromonas hydrophila

open access: yesAquaculture Reports
This study investigated the effects of Astragalus membranaceus by-product (AP) on feed quality, mold growth, and fish disease-resistant ability. Seven fish diets were prepared with gradient levels of AP (0, 1.0, 2.0, 4.0, 8.0, 16 and 32 %).
Gangfu Chen   +15 more
doaj   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

Agassiz, Garman, Albatross, and the Collection of Deep-sea Fishes [PDF]

open access: yes, 1999
The first of Alexander Agassiz’ voyages on the U.S. Fish Commission steamer Albatross in 1891 yielded significant scientific results. This paper reviews the background of the voyage, including the career path that led Agassiz to the back deck of the ...
Hartel, Karsten E.   +2 more
core  

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

Chronic hypoxia drives the occurrence of ferroptosis in liver of fat greening (Hexagrammos otakii) by activating HIF-1α and promoting iron production

open access: yesEcotoxicology and Environmental Safety
Background: Hypoxia caused by global climate change and human activities has become a growing concern eliciting serious effect and damages to aquatic animals.
Dongxu Gao   +7 more
doaj   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

open access: yesMolecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova   +26 more
wiley   +1 more source

Hypoxia induces pyroptosis and inflammation in the liver of fat greenling (Hexagrammos otakii)

open access: yesComparative Immunology Reports
In fisheries, hypoxia stress is one of the most common environmental stresses that often cause significant harm and losses to the aquaculture industry.
Yu Zhan   +8 more
doaj   +1 more source

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