Results 171 to 180 of about 1,577,442 (403)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Large-scale patterns in community structure of benthos and fish in the Barents Sea [PDF]

open access: hybrid, 2016
Edda Johannesen   +9 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Development and application of the adverse outcome pathway framework for understanding and predicting chronic toxicity: II. A focus on growth impairment in fish

open access: hybrid, 2014
Ksenia J. Groh   +9 more
openalex   +1 more source

Comprehensive phylogeny of ray-finned fishes (Actinopterygii) based on transcriptomic and genomic data

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
L. Hughes   +20 more
semanticscholar   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Potential effects of Sargassum kjellmanianum as a dietary supplement on the growth performance, immunity response, antioxidant status, and ammonia resistance of yellow catfish (Pelteobagrus fulvidraco)

open access: yesAquaculture Reports
This study aimed to investigate the potential effects of seaweed Sargassum kjellmanianum (SK) as a dietary supplement on the growth performance, blood biochemistry, immunology, antioxidants, and ammonia stress resistance of yellow catfish, Pelteobagrus ...
Peng Hu   +4 more
doaj   +1 more source

Pre-operational baseline studies of selected nearshore marine biota at the Diablo Canyon power plant site: 1979-1982 [PDF]

open access: yes, 1986
This is the final report of the California Department of Fish and Games intertidal and subtidal surveys of plants and animals in the vicinity of the Diablo Canyon Power Plant. These studies cover the period from 1979 through 1982.
Gotshall, Daniel W.   +4 more
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