Results 221 to 230 of about 1,531,875 (388)
Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides+13 more
wiley +1 more source
This study investigated the effects of Astragalus membranaceus by-product (AP) on feed quality, mold growth, and fish disease-resistant ability. Seven fish diets were prepared with gradient levels of AP (0, 1.0, 2.0, 4.0, 8.0, 16 and 32 %).
Gangfu Chen+15 more
doaj
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova+26 more
wiley +1 more source
Evolution of the Nonvisual and Visual Opsin Gene Repertoire in Ray-Finned Fishes. [PDF]
Policarpo M+3 more
europepmc +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero+8 more
wiley +1 more source
Incompatibility between two major innovations shaped the diversification of fish feeding mechanisms. [PDF]
Peoples N, Mihalitsis M, Wainwright PC.
europepmc +1 more source
Fish tropomyosin and fish nucleotropomyosin [PDF]
openaire +3 more sources
Landscapes to Riverscapes: Bridging the Gap between Research and Conservation of Stream Fishes
K. Fausch+3 more
semanticscholar +1 more source
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li+12 more
wiley +1 more source