Results 151 to 160 of about 892,982 (340)

OCCUPATIONAL CHARACTERISTICS, TECHNOLOGY USE AND OUTPUT DETERMINANTS AMONG FISHERFOLKS IN OGUN WATERSIDE AREA, OGUN STATE [PDF]

open access: yes
This study examines the occupational characteristics and technology options of capture fisheries in Ogun Waterside Local Government Area of Ogun State.
Akinleye, S.O.   +2 more
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Fishing Capacity and Harvest Rules [PDF]

open access: yes
In this note we consider the choice of optimum fishing capacity for fish stocks that vary at random. In models with stochastic variations of fish stocks, optimum fishing capacity is normally a decision variable separate from fishing effort.
Hannesson, Rognvaldur
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Fishing Technology and Optimal Distribution of Harvest Rates [PDF]

open access: yes
In this paper we analyze the optimal management of a joint ownership fishery exploitation model where agents use different fishing gears. As opposed to other works, we consider a model in which the fishing technology affects resource's growth not only ...
Escapa García, Marta, Prellezo, Raúl
core  

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