Results 171 to 180 of about 1,012,929 (386)

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

DETERMINING GROSS TONNAGE OF PURSE SEINERS USING A PHYSICAL MODELING APPROACH IN TEGAL, CENTRAL JAVA

open access: yesJurnal Teknologi Perikanan dan Kelautan
The research was carried out at the dock and shipping companies, PT. Indonesian Fisheries, PT. Tiara, and village cooperative unit (KUD) Karya Mina, at Tegal, Central Java, in October 2023. The research aims to determine the percentage change in shape of
Suharyanto Suharyanto   +4 more
doaj   +1 more source

APPLICATION OF HURDLE NEGATIVE BINOMIAL COUNT DATA MODEL TO DEMAND FOR BLACK BASS FISHING IN THE SOUTHEASTERN UNITED STATES. [PDF]

open access: yes
This paper identifies factors that influence the demand for a black bass fishing trip taken in the Southeastern U.S. using a double hurdle negative binomial count data model. The probability of fishing for a black bass is estimated in the first stage and
Bilgic, Abdulbaki   +1 more
core   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

open access: yesMolecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza   +3 more
wiley   +1 more source

FISHING FOR COMPLEMENTS

open access: yesNagoya Mathematical Journal
Abstract Given a presilting object in a triangulated category, we find necessary and sufficient conditions for the existence of a complement. This is done both for classic (pre)silting objects and for large (pre)silting objects. The key technique is the study of associated co-t-structures.
LIDIA ANGELERI HÜGEL   +2 more
openaire   +3 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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