Results 171 to 180 of about 892,982 (340)
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Reconstructing the spatial and temporal dynamics of Ecuador's artisanal small-scale fisheries from fishers' perspective. [PDF]
Peñaherrera-Palma CR +6 more
europepmc +1 more source
Whale-watching and Herring Fishing: Joint or Independent Production? [PDF]
The effects of "localized depletion" of a pelagic fishery (herring) on a non-extractive marine activity (tourism) are investigated. Proponents of the localized depletion theory claim that intense fishing effort can lead to areas that are unsuitable for ...
Lee, Min-Yang A.
core +1 more source
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Multivariate Gas Sensor E-Nose System with PARAFAC and Machine Learning Modeling for Quantifying and Classifying the Impact of Fishing Gears. [PDF]
Silva-Alvarado VL, Lloret J.
europepmc +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Subsistence fishing patterns near food deserts. [PDF]
Swinea SH +5 more
europepmc +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source

